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孕期及哺乳期青光眼治疗进展:当代管理策略与前瞻性治疗进展

Advancing Glaucoma Treatment During Pregnancy and Breastfeeding: Contemporary Management Strategies and Prospective Therapeutic Developments.

作者信息

Salvetat Maria Letizia, Toro Mario Damiano, Pellegrini Francesco, Scollo Paolo, Malaguarnera Roberta, Musa Mutali, Mereu Liliana, Tognetto Daniele, Gagliano Caterina, Zeppieri Marco

机构信息

Department of Ophthalmology, Azienda Sanitaria Friuli Occidentale, Via Montereale 24, 33170 Pordenone, Italy.

Eye Clinic, Public Health Department, Federico II University, Via Pansini 5, 80131 Naples, Italy.

出版信息

Biomedicines. 2024 Nov 25;12(12):2685. doi: 10.3390/biomedicines12122685.

Abstract

The management of glaucoma in pregnancy and breastfeeding requires a careful evaluation of treatment choices to guarantee the well-being of both the mother and the developing fetus. This review explores the intricacies of controlling glaucoma in pregnant and breastfeeding women, including a comprehensive overview of existing glaucoma treatment methods, clinical guidelines, and future therapeutic approaches. The efficacy and safety profiles of traditional treatment approaches, such as topical and systemic medicines and surgical treatments, are evaluated specifically about their use during pregnancy and breastfeeding. The significance of personalized treatment programs to achieve a balance between controlling intraocular pressure and ensuring the safety of the fetus and the newborn and the importance of a multidisciplinary approach that includes ophthalmologists, obstetricians, and other healthcare experts are underlined. Non-pharmacological therapies, lifestyle adjustments, and the importance of patient education in the management of glaucoma during pregnancy and the post-partum period are also examined. Advancing our comprehension of and strategy toward glaucoma can reduce the effects of glaucoma on maternal, fetal, and newborn well-being.

摘要

妊娠和哺乳期青光眼的管理需要仔细评估治疗选择,以确保母亲和发育中胎儿的健康。本综述探讨了妊娠和哺乳期妇女控制青光眼的复杂性,包括对现有青光眼治疗方法、临床指南和未来治疗方法的全面概述。特别评估了传统治疗方法(如局部和全身用药以及手术治疗)在妊娠和哺乳期使用时的疗效和安全性。强调了个性化治疗方案对于在控制眼压与确保胎儿和新生儿安全之间取得平衡的重要性,以及包括眼科医生、产科医生和其他医疗保健专家在内的多学科方法的重要性。还研究了非药物疗法、生活方式调整以及患者教育在妊娠和产后青光眼管理中的重要性。增进我们对青光眼的理解和应对策略可以减少青光眼对母亲、胎儿和新生儿健康的影响。

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本文引用的文献

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[Ophthalmic agents during pregnancy].[孕期眼科用药]
Ophthalmologie. 2024 Apr;121(4):333-348. doi: 10.1007/s00347-024-02025-5. Epub 2024 Apr 8.
10
Trabeculectomy in first trimester of pregnancy: A case report.妊娠早期小梁切除术:一例报告。
Eur J Ophthalmol. 2023 Nov;33(6):NP49-NP52. doi: 10.1177/11206721231158060. Epub 2023 Mar 2.

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