Shen Furong, Bao Lei
Department of Pediatrics, University-Town Hospital of Chongqing Medical University, Chongqing 401331, China.
Department of Neonatology, Ministry of Education Key Laboratory of Child Development and Disorders, Key Laboratory of Pediatrics, Children's Hospital of Chongqing Medical University, Chongqing 400014, China.
Children (Basel). 2024 Dec 16;11(12):1522. doi: 10.3390/children11121522.
To investigate the effects of music intervention on the vital signs, weight gain, feeding, hospital stays, and cost of premature infants.
100 premature infants were randomized into two groups: the experimental group (given music for 30 min at a time, once every day until discharge) and the control group (without music). To compare the vital signs (RR, HR, SPO) before, during, and after the music intervention, as well as the weight gain and feeding, follow up to 3 months after discharge.
Although respiratory rate (RR) showed a decreasing trend at certain time points during and after music exposure, these changes did not reach statistical significance after adjusting for multiple comparisons. The experimental group had a shorter time to regain birth weight (6.07 ± 2.47 days) compared to the control group (8.93 ± 4.31 days) and a shorter time of intravenous nutrition (8.6 ± 3.87 days vs. 11.66 ± 5.85 days). The experimental group also exhibited a lower fasting rate, a faster-sucking speed, a lower hospital stay (10.36 ± 4.36 days vs. 12.46 ± 5.73 days), lower cost, higher NBNA scores, and a lower re-hospitalization rate within 3 months after the first discharge.
Early music intervention may contribute to the growth and development of preterm infants, improve feeding, reduce hospitalization duration and costs, and improve short-term prognosis, though effects on respiratory rate require further study with a larger sample size.
探讨音乐干预对早产儿生命体征、体重增加、喂养情况、住院时间及费用的影响。
将100例早产儿随机分为两组：实验组（每次给予音乐干预30分钟，每天1次直至出院）和对照组（不给予音乐干预）。比较音乐干预前、干预期间及干预后的生命体征（呼吸频率、心率、血氧饱和度），以及体重增加和喂养情况，出院后随访3个月。
尽管在音乐暴露期间及之后的某些时间点呼吸频率呈下降趋势，但在进行多重比较校正后，这些变化未达到统计学意义。与对照组（8.93±4.31天）相比，实验组恢复出生体重的时间更短（6.07±2.47天），静脉营养时间更短（8.6±3.87天 vs. 11.66±5.85天）。实验组还表现出较低的禁食率、较快的吸吮速度、较短的住院时间（10.36±4.36天 vs. 12.46±5.73天）、较低的费用、较高的新生儿行为神经评分（NBNA）以及首次出院后3个月内较低的再住院率。
早期音乐干预可能有助于早产儿的生长发育，改善喂养情况，缩短住院时间并降低费用，改善短期预后，尽管对呼吸频率的影响需要更大样本量的进一步研究。
