Simon Sonja C S, Bibi Igor, Schaffert Daniel, Benecke Johannes, Martin Niklas, Leipe Jan, Vladescu Cristian, Olsavszky Victor
Department of Dermatology, Venereology and Allergology, University Medical Center and Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany.
Department of Medicine V, Division of Rheumatology, University Medical Center and Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany.
Bioengineering (Basel). 2024 Dec 15;11(12):1272. doi: 10.3390/bioengineering11121272.
The COVID-19 pandemic severely impacted healthcare systems, affecting patient outcomes and resource allocation. This study applied automated machine learning (AutoML) to analyze key health outputs, such as discharge conditions, mortality, and COVID-19 cases, with the goal of improving responses to future crises.
AutoML was used to train and validate models on an ICD-10 dataset covering the first wave of COVID-19 in Romania (January-September 2020).
For discharge outcomes, Light Gradient Boosted models achieved an F1 score of 0.9644, while for mortality 0.7545 was reached. A Generalized Linear Model blender achieved an F1 score of 0.9884 for "acute or emergency" cases, and an average blender reached 0.923 for COVID-19 cases. Older age, specific hospitals, and oncology wards were less associated with improved recovery rates, while mortality was linked to abnormal lab results and cardiovascular/respiratory diseases. Patients admitted without referral, or patients in hospitals in the central region and the capital region of Romania were more likely to be acute cases. Finally, counties such as Argeş (South-Muntenia) and Brașov (Center) showed higher COVID-19 infection rates regardless of age.
AutoML provided valuable insights into patient outcomes, highlighting variations in care and the need for targeted health strategies for both COVID-19 and other health challenges.
新冠疫情对医疗系统造成了严重影响,影响了患者的治疗结果和资源分配。本研究应用自动化机器学习(AutoML)来分析关键的健康产出,如出院情况、死亡率和新冠病例,目的是改善对未来危机的应对措施。
使用AutoML在一个涵盖罗马尼亚第一波新冠疫情(2020年1月至9月)的国际疾病分类第十版(ICD - 10)数据集上训练和验证模型。
对于出院结果,轻梯度提升模型的F1分数达到0.9644,而死亡率的F1分数为0.7545。一个广义线性模型混合器在“急性或紧急”病例上的F1分数达到0.9884,对于新冠病例,平均混合器的F1分数为0.923。年龄较大、特定医院和肿瘤科病房与康复率提高的关联性较小,而死亡率与异常实验室结果以及心血管/呼吸系统疾病有关。未经转诊入院的患者,或罗马尼亚中部地区和首都地区医院的患者更有可能是急性病例。最后,阿尔杰什县(南蒙特尼亚)和布拉索夫县(中部)等县无论年龄大小,新冠感染率都较高。
AutoML为患者治疗结果提供了有价值的见解,突出了护理方面的差异以及针对新冠疫情和其他健康挑战制定有针对性的健康策略的必要性。