Karampinis Emmanouil, Toli Olga, Georgopoulou Konstantina-Eirini, Papadopoulou Maria-Myrto, Vardiampasi Anna, Zafiriou Efterpi, Lazaridou Elizabeth, Apalla Zoe, Lallas Aimilios, Behera Biswanath, Errichetti Enzo
Second Dermatology Department, School of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Department of Dermatology, Faculty of Medicine, School of Health Sciences, University General Hospital of Larissa, University of Thessaly, 41110 Larissa, Greece.
Life (Basel). 2024 Dec 4;14(12):1604. doi: 10.3390/life14121604.
This literature review aims to comprehensively evaluate the clinical and dermoscopic presentations of common pediatric diseases among children with skin of color (SoC) while also addressing potential variations based on racial backgrounds. This review encompasses various conditions, such as nevi subtypes, viral infections, infestations, and inflammatory dermatoses, as well as hair diseases and abnormal vascular formations, occurring in pediatric populations. Overall, we identified 7 studies on nevi subtypes, 24 studies on skin infections, 6 on inflammatory dermatoses, 10 on hair diseases and disorders, and 14 on miscellaneous disorders that also satisfied our SoC- and race-specific criteria. In case of no results, we assumed that dermoscopic findings are similar between SoC adults and children, confirming the hypothesis with our cases of dark-skinned Indian child patients. Inflammatory dermatoses such as psoriasis, eczema, and cutaneous mastocytosis, as well as skin infections like cutaneous leishmaniasis, appear with brownish backgrounds or exhibit dark structures more frequently than the respective dermoscopy images of Caucasian populations. Dermoscopy traits such as erythema in tinea capitis are uncommon or even absent on a dark-colored scalp, while a dark skin tone often obscures many characteristic features, such as dark and yellow dots in alopecia areata and even parts of an intradermal parasite in the case of scabies. Race-specific traits were also observed, such as corkscrew hair in tinea capitis, primarily seen in patients of African origin. Many dermoscopic images are consistent between SoC and non-SoC in various skin lesions, including vascular anomalies, juvenile xanthogranuloma, mastocytoma, and viral skin lesions like molluscum contagiosum, as well as in various hair disorders such as trichotillomania, while tinea capitis displays the most diverse reported dermoscopic features across SoC- and race-specific studies.
本综述旨在全面评估有色人种儿童常见儿科疾病的临床和皮肤镜表现,同时探讨基于种族背景的潜在差异。本综述涵盖了儿科人群中出现的各种病症,如痣的亚型、病毒感染、寄生虫感染、炎症性皮肤病、毛发疾病以及异常血管形成。总体而言,我们确定了7项关于痣亚型的研究、24项关于皮肤感染的研究、6项关于炎症性皮肤病的研究、10项关于毛发疾病的研究以及14项关于其他杂症的研究,这些研究均符合我们针对有色人种和种族的特定标准。在没有相关结果的情况下,我们假设有色人种成人和儿童的皮肤镜表现相似,并通过我们的深色皮肤印度儿童患者病例来验证这一假设。与白种人群的相应皮肤镜图像相比,银屑病、湿疹和皮肤肥大细胞增多症等炎症性皮肤病以及皮肤利什曼病等皮肤感染,在深色背景下出现或表现为深色结构的频率更高。头癣中的红斑等皮肤镜特征在深色头皮上并不常见甚至不存在,而深肤色往往会掩盖许多特征,如斑秃中的黑点和黄点,甚至疥疮病例中的皮内寄生虫部分。还观察到了种族特异性特征,如头癣中的螺旋状毛发,主要见于非洲裔患者。在各种皮肤病变中,包括血管异常、幼年黄色肉芽肿、肥大细胞瘤以及传染性软疣等病毒皮肤病变,以及拔毛癖等各种毛发疾病中,有色人种和非有色人种的许多皮肤镜图像是一致的,而头癣在针对有色人种和种族的特定研究中显示出最多样化的皮肤镜特征报告。