Batres Laura, Arroyo-Del Arroyo Cristina, Bodas-Romero Julia, Carracedo Gonzalo
Ocupharm Research Group, Department of Optometry and Vision, Faculty of Optics and Optometry, Complutense University of Madrid, 28037 Madrid, Spain.
IOBA (Institute of Applied Ophthalmobiology), University of Valladolid, 47002 Valladolid, Spain.
J Clin Med. 2024 Dec 12;13(24):7567. doi: 10.3390/jcm13247567.
: The objective of this study was to examine the trend of treatment zone (TZ) decentration over 12 months of orthokeratology (OK) wear using two Corneal Refractive Therapy (CRT) lens designs: standard (STD) and dual axis (DA). : A prospective, randomized, longitudinal study was conducted at the Optometry Clinic of the Complutense University of Madrid. Subjects were randomly fitted with an STD design or DA design in one of the eyes. Refraction, uncorrected visual acuity (VA), and corneal topography were performed at baseline and after 1 night, 1 week, and 1, 3, 6, and 12 months of lens wear. Subjects requiring lens parameter adjustments or replacements after 3 months were excluded. Decentration was measured by subtracting pre-OK from post-OK tangential curvature maps at each visit, with decentration distance and corneal optical TZ being measured using MATLAB. Correlations between decentration and visual acuity (VA) were also analyzed. : A total of 30 healthy children (17 females and 13 males) with a mean age of 12.83 ± 2.42 years (range: 8-17 years) completed all the visits. No statistically significant differences ( > 0.05) were found between lens designs in horizontal, vertical, nor total decentration through the visits. However, for the STD design, horizontal and total decentration increased significantly at the last visit ( < 0.05). For the DA design, no significant differences were found over time ( > 0.05). No correlation was found between decentration and VA. : Total decentration in both lens designs was similar throughout one year of follow-up. The standard design tended to decenter horizontally during the last 6 months, while the dual-axis design maintained consistent decentration throughout the year.
本研究的目的是使用两种角膜塑形术（OK）镜片设计：标准（STD）和双轴（DA），来检查在12个月的角膜塑形术佩戴期间治疗区（TZ）偏心的趋势。
在马德里康普顿斯大学验光诊所进行了一项前瞻性、随机、纵向研究。受试者的一只眼睛被随机配适STD设计或DA设计的镜片。在基线以及佩戴镜片1晚、1周、1、3、6和12个月后进行验光、裸眼视力（VA）和角膜地形图检查。排除在3个月后需要调整镜片参数或更换镜片的受试者。每次就诊时，通过从佩戴OK镜片后的切向曲率图中减去佩戴前的切向曲率图来测量偏心，使用MATLAB测量偏心距离和角膜光学治疗区。还分析了偏心与视力（VA）之间的相关性。
共有30名健康儿童（17名女性和13名男性）完成了所有就诊，平均年龄为12.83±2.42岁（范围：8 - 17岁）。在整个就诊过程中，两种镜片设计在水平、垂直或总偏心方面均未发现统计学上的显著差异（>0.05）。然而，对于STD设计，在最后一次就诊时水平和总偏心显著增加（<0.05）。对于DA设计，随时间未发现显著差异（>0.05）。未发现偏心与VA之间存在相关性。
在一年的随访中，两种镜片设计的总偏心情况相似。标准设计在最后6个月倾向于水平偏心，而双轴设计在全年保持一致的偏心。
