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夜间角膜塑形镜验配偏中心对角膜地形图重塑的影响。

Influence of overnight orthokeratology lens fitting decentration on corneal topography reshaping.

作者信息

Chen Jiaojie, Huang Wei, Zhu Rong, Jiang Jun, Li Yiyu

机构信息

1School of Optometry and Ophthalmology, WenZhou Medical University, WenZhou, ZheJiang China.

2Eye Hospital of Wenzhou Medical University, 270 West Xueyuan Road, Wenzhou, Zhejiang 325027 China.

出版信息

Eye Vis (Lond). 2018 Mar 15;5:5. doi: 10.1186/s40662-018-0100-7. eCollection 2018.

Abstract

BACKGROUND

This retrospective study was designed to investigate the sole influence of orthokeratology (OK) lens fitting decentration on the Zernike coefficients of the reshaped anterior corneal surface.

METHODS

This study comprised a review of 106 right eyes and measurements of corneal topography both before OK and at 1-month follow-up visit. A routine was designed to calculate local corneal surface astigmatism and assist the determination of OK lens fitting decentration from pupil center. The pupil-centered corneal Zernike coefficients of baseline (PCCB) and post-treatment (PCCP) were calculated. Meanwhile, the OK-lens-centered corneal Zernike coefficients of post-treatment (OCCP) were also calculated and considered as the presumptive ideal fitting group without decentration. Relationships between lens fitting decentration and the change of Zernike coefficients including (PCCP - PCCB) and (PCCP - OCCP) were analyzed.

RESULTS

Patients with a mean age of 11 ± 2.36 years old had an average spherical equivalent refractive error of -3.52 ± 1.06 D before OK. One month after treatment, OK lens fitting decentration from pupil center was 0.68 ± 0.35 mm. RMS of 3rd-order ( < 0.05), RMS of 4th-order ( < 0.001) and RMS of total high order ( < 0.001) corneal Zernike coefficients were increased in PCCP by comparing with OCCP, which was solely caused by lens fitting decentration. Nevertheless, no significant difference was observed in [Formula: see text] ( > 0.05). For the high order corneal Zernike coefficients in (PCCP - OCCP), radial distance of decentration was correlated with [Formula: see text] ( = -0.296,  < 0.05), [Formula: see text] ( = -0.396,  < 0.001), and [Formula: see text] ( = 0.449,  < 0.001), horizontal decentration was significantly correlated with [Formula: see text] ( = 0.901,  < 0.001) and [Formula: see text] ( = 0.340,  < 0.001), and vertical decentration was significantly correlated with [Formula: see text] ( = 0.904,  < 0.001).

CONCLUSIONS

OK lens fitting decentration within 1.5 mm hardly influenced the change of corneal spherical power for myopia correction, but significantly induced additional corneal high order Zernike coefficients including [Formula: see text], [Formula: see text], [Formula: see text], and [Formula: see text].

摘要

背景

本回顾性研究旨在调查角膜塑形术(OK)镜片配适偏心对重塑前角膜表面的泽尼克系数的单一影响。

方法

本研究包括对106只右眼的回顾以及在OK治疗前和随访1个月时的角膜地形图测量。设计了一个程序来计算局部角膜表面散光,并协助确定OK镜片相对于瞳孔中心的配适偏心。计算了基线时以瞳孔为中心的角膜泽尼克系数(PCCB)和治疗后的系数(PCCP)。同时,还计算了治疗后以OK镜片为中心的角膜泽尼克系数(OCCP),并将其视为无偏心的假定理想配适组。分析了镜片配适偏心与泽尼克系数变化之间的关系,包括(PCCP - PCCB)和(PCCP - OCCP)。

结果

平均年龄为11±2.36岁的患者在OK治疗前平均等效球镜屈光不正为-3.52±1.06D。治疗1个月后,OK镜片相对于瞳孔中心的配适偏心为0.68±0.35mm。与OCCP相比,PCCP中三阶(<0.05)、四阶(<0.001)和总高阶(<0.001)角膜泽尼克系数的均方根增加,这完全是由镜片配适偏心引起的。然而,在[公式:见原文]中未观察到显著差异(>0.05)。对于(PCCP - OCCP)中的高阶角膜泽尼克系数,偏心的径向距离与[公式:见原文](=-0.296,<0.05)、[公式:见原文](=-0.396,<0.001)和[公式:见原文](=0.449,<0.001)相关,水平偏心与[公式:见原文](=0.901,<0.001)和[公式:见原文](=0.340,<0.001)显著相关,垂直偏心与[公式:见原文](=0.904,<0.001)显著相关。

结论

1.5mm以内的OK镜片配适偏心对近视矫正中角膜球镜度的变化影响不大,但会显著诱导额外的角膜高阶泽尼克系数,包括[公式:见原文]、[公式:见原文]、[公式:见原文]和[公式:见原文]。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2998/5853138/0c4e2b3a96cb/40662_2018_100_Fig1_HTML.jpg

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