Oliver-Gutierrez David, Gutuleac Liliana, Anglada-Masferrer Natalia, Segura-Duch Gloria, Martin Sara, Bisbe Laia, Martín-Gómez María Teresa, Zapata Miguel Ángel, Puig Javier José
Ophthalmology Department, Hospital Universitari Vall d'Hebron, 08035 Barcelona, Spain.
Ophthalmology Department, Innova Ocular Verte Barcelona, 08006 Barcelona, Spain.
J Clin Med. 2024 Dec 19;13(24):7775. doi: 10.3390/jcm13247775.
: This study evaluates the effectiveness of therapeutic keratoplasty for fungal keratitis and explores the diagnosis and management challenges of this infectious corneal disease. We retrospectively analyzed therapeutic keratoplasty cases at a tertiary hospital for keratitis when standard treatments failed. : Five cases of keratitis, unresponsive to typical antifungal treatments, required keratoplasty due to fast progression and diagnostic difficulties. Post-surgery, all patients had infection resolution without recurrence, but some complications like anterior chamber leakage, graft rejection, and ocular hypertension were managed effectively. Final visual acuity ranged from 0.9 to finger counting. : keratitis, often resistant to conventional therapies, may necessitate keratoplasty for resolution. This intervention is crucial for positive outcomes, emphasizing the need for prompt and effective management to prevent severe surgical measures and preserve ocular health.
本研究评估治疗性角膜移植术治疗真菌性角膜炎的有效性，并探讨这种感染性角膜疾病的诊断和管理挑战。我们回顾性分析了一家三级医院在标准治疗失败时针对角膜炎进行治疗性角膜移植术的病例。5例对典型抗真菌治疗无反应的角膜炎患者，由于病情快速进展和诊断困难而需要进行角膜移植术。术后，所有患者感染均得到解决且无复发，但一些并发症如前房渗漏、移植排斥反应和高眼压症得到了有效处理。最终视力范围从0.9到数指。角膜炎通常对传统疗法有抵抗性，可能需要进行角膜移植术来解决。这种干预对于取得良好结果至关重要，强调需要及时有效的管理以避免采取严厉的手术措施并保护眼部健康。
