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较高的查尔森合并症指数是老年人在低温时期髋部骨折的危险因素:一项横断面研究。

A Higher Charlson Comorbidity Index Is a Risk Factor for Hip Fracture in Older Adults During Low-Temperature Periods: A Cross-Sectional Study.

作者信息

Chiang Ming-Hsiu, Kuo Yi-Jie, Huang Shu-Wei, Tran Duy Nguyen Anh, Chuang Tai-Yuan, Chen Yu-Pin, Lin Chung-Ying

机构信息

Department of General Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833, Taiwan.

Department of Orthopedics, Wan Fang Hospital, Taipei Medical University, Taipei 116, Taiwan.

出版信息

Medicina (Kaunas). 2024 Nov 28;60(12):1962. doi: 10.3390/medicina60121962.

DOI:10.3390/medicina60121962
PMID:39768843
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11677170/
Abstract

: The incidence of hip fractures is increasing, and there have been reports linking cold weather to a higher risk of fractures. This study aimed to evaluate clinical variables in hip fracture patients who may predispose them to such fractures under different temperatures. : This is a cross-sectional study conducted at a single medical center, enrolling older adults (≥60 years) who had experienced a hip fracture. Comprehensive clinical histories and detailed information regarding each patient's hip fracture were obtained. All meteorological data were extracted from the Taiwan Central Weather Bureau database. Multiple clinical parameters that may have a close connection with the temperature at which the hip fracture occurred were screened. Statistical analysis involved using the Pearson correlation test or the independent Student's test, followed by generalized estimating equation analysis. : The cohort comprised 506 older adults with hip fractures. Initial univariate analysis revealed that a history of past cerebrovascular diseases, Charlson Comorbidity Index, patient age, and preinjury Barthel Index were significantly related to the temperature at which the hip fractures occurred. The generalized estimating equation analysis indicated that only the Charlson Comorbidity Index had a considerably inverse association with temperature. This finding suggests that for older adults with a higher Charlson Comorbidity Index, hip fractures tend to occur at lower temperatures and vice versa. : Comorbidities are the only clinical concern that predisposes older adults to hip fractures under colder temperatures. This epidemiological finding could guide future patient education and hip fracture prevention programs.

摘要

髋部骨折的发病率正在上升,并且有报告将寒冷天气与更高的骨折风险联系起来。本研究旨在评估髋部骨折患者在不同温度下可能使其易患此类骨折的临床变量。 这是一项在单一医疗中心进行的横断面研究,纳入了经历过髋部骨折的老年人(≥60岁)。获取了每位患者髋部骨折的全面临床病史和详细信息。所有气象数据均从台湾中央气象局数据库中提取。筛选了可能与髋部骨折发生时的温度密切相关的多个临床参数。统计分析采用Pearson相关检验或独立样本t检验,随后进行广义估计方程分析。 该队列包括506名髋部骨折的老年人。初步单因素分析显示,既往脑血管疾病史、Charlson合并症指数、患者年龄和伤前Barthel指数与髋部骨折发生时的温度显著相关。广义估计方程分析表明,只有Charlson合并症指数与温度有显著的负相关。这一发现表明,对于Charlson合并症指数较高的老年人,髋部骨折往往在较低温度下发生,反之亦然。 合并症是在较冷温度下使老年人易患髋部骨折的唯一临床相关因素。这一流行病学发现可为未来的患者教育和髋部骨折预防计划提供指导。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8c9/11677170/43f2c5f843ee/medicina-60-01962-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8c9/11677170/43f2c5f843ee/medicina-60-01962-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8c9/11677170/43f2c5f843ee/medicina-60-01962-g001.jpg

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本文引用的文献

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New-onset stroke on the risk of hip fracture: the Kailuan cohort study in China.中国开滦队列研究:新发脑卒中与髋部骨折风险。
BMC Public Health. 2023 May 22;23(1):925. doi: 10.1186/s12889-023-15787-5.
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Skeletal Muscle Changes in the First Three Months of Stroke Recovery: A Systematic Review.脑卒中康复头 3 个月的骨骼肌变化:系统评价。
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寒冷环境温度与骨折风险和死亡率的关联:来自挪威的全国数据-挪威流行病学骨质疏松研究(NOREPOS)研究。
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Effect of meteorological factors and air pollutants on fractures: a nationwide population-based ecological study.气象因素和空气污染物对骨折的影响:一项全国范围内基于人群的生态学研究。
BMJ Open. 2021 Jun 11;11(6):e047000. doi: 10.1136/bmjopen-2020-047000.
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