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[具体物种]引起的感染的抗菌药物敏感性模式及抗菌治疗

Antimicrobial Susceptibility Patterns and Antimicrobial Therapy of Infections Caused by Species.

作者信息

Huang Chienhsiu

机构信息

Department of Internal medicine, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chiayi 62247, Taiwan.

出版信息

Medicina (Kaunas). 2024 Dec 2;60(12):1990. doi: 10.3390/medicina60121990.

Abstract

: species have become significant sources of infections acquired in hospital settings and are commonly linked to high mortality rates. Antimicrobial resistance can be influenced by species, geographical location, antimicrobial susceptibility testing methods, and the time of bacterial isolation. There are distinct antimicrobial susceptibility patterns among species, and the investigation into potential antibiotic susceptibility variations among species is beneficial. There is no guidance on the treatment of species infections in the literature. Consequently, the purpose of this review was to elaborate on the antimicrobial susceptibility patterns of species through a scoping review of existing studies on the antibiograms of the species and on the illness caused by species. : A comprehensive literature search in PubMed and Web of Science between 1 January 2000 and 30 April 2024 identified all studies, including those that examined antimicrobial susceptibility patterns and antimicrobial therapy of infections caused by species. I considered studies on antimicrobial susceptibility testing for species in which only broth microdilution methods and agar dilution methods were used. : The sensitivity levels of to piperacillin-tazobactam (5-100%), ciprofloxacin (0-43.4%), levofloxacin (30-81.8%), trimethoprim-sulfamethoxazole (0-100%), tigecycline (15-100%), minocycline (60-100%), and rifampicin (94-100%) varied. The sensitivity levels of to piperacillin-tazobactam (3.3-93.3%), ciprofloxacin (1-75%), levofloxacin (12-100%), trimethoprim-sulfamethoxazole (1.02-96.7%), tigecycline (0-52.2%), minocycline (97.5-100%), and rifampicin (20.5-96%) varied. The sensitivity levels of to piperacillin-tazobactam (41.6-94.0%), ciprofloxacin (14-75%), levofloxacin (77.0-100%), trimethoprim-sulfamethoxazole (18.0-100%), tigecycline (50%), minocycline (100%), and rifampicin (66-85.7%) varied. : The majority of the isolates of species were susceptible to minocycline and rifampin. This issue requires professional knowledge integration and treatment recommendations.

摘要

某些物种已成为医院获得性感染的重要来源,通常与高死亡率相关。抗菌药物耐药性会受到物种、地理位置、抗菌药物敏感性测试方法以及细菌分离时间的影响。不同物种之间存在明显的抗菌药物敏感性模式,对不同物种间潜在的抗生素敏感性差异进行研究是有益的。文献中没有关于某些物种感染治疗的指导。因此,本综述的目的是通过对现有关于某些物种抗菌谱及由某些物种引起疾病的研究进行范围综述,详细阐述某些物种的抗菌药物敏感性模式。:在2000年1月1日至2024年4月30日期间,在PubMed和Web of Science上进行了全面的文献检索,确定了所有研究,包括那些检查某些物种引起感染的抗菌药物敏感性模式和抗菌治疗的研究。我考虑了仅使用肉汤微量稀释法和琼脂稀释法进行某些物种抗菌药物敏感性测试的研究。:某些物种对哌拉西林 - 他唑巴坦(5 - 100%)、环丙沙星(0 - 43.4%)、左氧氟沙星(30 - 81.8%)、复方新诺明(0 - 100%)、替加环素(15 - 100%)、米诺环素(60 - 100%)和利福平(94 - 100%)的敏感性水平各不相同。某些物种对哌拉西林 - 他唑巴坦(3.3 - 93.3%)、环丙沙星(1 - 75%)、左氧氟沙星(12 - 100%)、复方新诺明(1.02 - 96.7%)、替加环素(0 - 52.2%)、米诺环素(97.5 - 100%)和利福平(20.5 - 96%)的敏感性水平各不相同。某些物种对哌拉西林 - 他唑巴坦(41.6 - 94.0%)、环丙沙星(14 - 75%)、左氧氟沙星(77.0 - 100%)、复方新诺明(18.0 - 100%)、替加环素(50%)、米诺环素(100%)和利福平(66 - 85.7%)的敏感性水平各不相同。:大多数某些物种的分离株对米诺环素和利福平敏感。这个问题需要专业知识整合和治疗建议。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b82/11727692/e5361abfe5ee/medicina-60-01990-g001.jpg

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