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甲氧苄啶-磺胺甲恶唑(TMP-SMZ)与依拉环素联合治疗嗜沫寡养单胞菌所致肺部感染:1例报告

Combination Therapy of Trimethoprim-Sulfamethoxazole (TMP-SMZ) and Eravacycline for Treating Elizabethkingia anophelis-Induced Pulmonary Infections: A Case Report.

作者信息

Wei Qimei, Zuo Wenxia, Cong Rong, Luo Kun, Dong Shanshan

机构信息

Department of Clinical Laboratory, Wuhan Asia Heart Hospital, Wuhan, 430022, People's Republic of China.

Department of Cardiac Critical Care Medicine, Wuhan Asia Heart Hospital, Wuhan, 430022, People's Republic of China.

出版信息

Infect Drug Resist. 2024 Nov 3;17:4825-4832. doi: 10.2147/IDR.S490902. eCollection 2024.

Abstract

is an opportunistic pathogen that causes serious life-threatening infections. In this report, we describe a case of pulmonary infection caused by in a young female patient, following cardiac surgery, which was successfully treated with a combination of trimethoprim-sulfamethoxazole (TMP-SMZ) and eravacycline. Additionally, this report provides a summary of high-risk factors for infection, clinical manifestations, and therapeutic options. Given the high degree of antimicrobial drug resistance of the organism and the fact that inappropriate empirical antimicrobial therapy constitutes a risk factor for mortality, our case serves as a valuable reference for similar cases, highlighting potential strategies for effective management.

摘要

是一种机会致病菌,可引起严重的危及生命的感染。在本报告中,我们描述了一名年轻女性患者在心脏手术后由 引起的肺部感染病例,该病例通过甲氧苄啶-磺胺甲恶唑(TMP-SMZ)和依拉环素联合治疗成功治愈。此外,本报告还总结了 感染的高危因素、临床表现和治疗选择。鉴于该病原体的高度抗菌药物耐药性以及不适当的经验性抗菌治疗是死亡的危险因素这一事实,我们的病例为类似病例提供了有价值的参考,突出了有效管理的潜在策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/990b/11542489/36cc3a380c1b/IDR-17-4825-g0001.jpg

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