Xu Xinxin, Mo Qingxian, Cai Zebin, Jiang Qing, Zhou Danman, Yi Jicai
College of Life Sciences, South China Agricultural University, Guangzhou 510642, China.
Int J Mol Sci. 2024 Dec 10;25(24):13237. doi: 10.3390/ijms252413237.
Rice (), a globally significant staple crop, is crucial for ensuring human food security due to its high yield and quality. However, the intensification of industrial activities has resulted in escalating cadmium (Cd) pollution in agricultural soils, posing a substantial threat to rice production. To address this challenge, this review comprehensively analyzes rice promoters, with a particular focus on identifying and characterizing key -regulatory elements (CREs) within them. By elucidating the roles of these CREs in regulating Cd stress response and accumulation in rice, we aim to establish a scientific foundation for developing rice varieties with reduced Cd accumulation and enhanced tolerance. Furthermore, based on the current understanding of plant promoters and their associated CREs, our study identifies several critical research directions. These include the exploration of tissue-specific and inducible promoters, as well as the discovery of novel CREs specifically involved in the mechanisms of Cd uptake, transport, and detoxification in rice. Our findings not only contribute to the existing knowledge base on genetic engineering strategies for mitigating Cd contamination in rice but pave the way for future research aimed at enhancing rice's resilience to Cd pollution, ultimately contributing to the safeguarding of global food security.
水稻作为一种全球重要的主食作物，因其高产和优质，对于确保人类粮食安全至关重要。然而，工业活动的加剧导致农业土壤中镉（Cd）污染不断升级，对水稻生产构成重大威胁。为应对这一挑战，本综述全面分析了水稻启动子，特别着重于识别和表征其中的关键调控元件（CREs）。通过阐明这些CREs在调节水稻镉胁迫响应和积累中的作用，我们旨在为培育镉积累量降低且耐受性增强的水稻品种奠定科学基础。此外，基于目前对植物启动子及其相关CREs的认识，我们的研究确定了几个关键的研究方向。这些方向包括对组织特异性和诱导型启动子的探索，以及发现专门参与水稻镉吸收、转运和解毒机制的新型CREs。我们的研究结果不仅有助于丰富有关减轻水稻镉污染的基因工程策略的现有知识库，还为未来旨在增强水稻对镉污染抗性的研究铺平道路，最终为保障全球粮食安全做出贡献。
