Liu Yang, Liu Shuaihua, Zhang Qiang, Tian Guanghui
School of Chemistry and Environment Science, Shaanxi University of Technology, Hanzhong 723001, China.
Shaanxi Key Laboratory of Catalysis, Shaanxi University of Technology, Hanzhong 723001, China.
Molecules. 2024 Dec 23;29(24):6055. doi: 10.3390/molecules29246055.
As a small-molecule gelator used as a stabilizer in gel emulsions, it has numerous advantages, such as low dosage, independence from phase ratios, and ease of control. In this study, a cholesterol derivative (CSA) was designed and synthesized to be used as a stabilizer for gel emulsions. Gelation experiments demonstrated that this small molecule could gelate various organic solvents, including linear alkanes, toluene, isoamyl alcohol, and acetone. Based on these gelation experiments, a series of gel emulsions were prepared with water as the dispersed phase and an organic solvent immiscible with water as the continuous phase. Finally, the gelation behavior of the gelator/water/toluene and gelator/water/cyclohexane systems was investigated, exploring the effects of different systems and varying water content within the same system on the structure and stability of the gel emulsions. Studies have shown that the gel emulsion prepared from the gelator/water/toluene system exhibits superior stability, likely due to the molecular self-assembly behavior of this cholesterol derivative exhibited in the water/toluene biphasic system. The research results provide a basis for using gel emulsions as templates to prepare porous materials and adjust their internal structure, ultimately laying a solid foundation for applying these porous materials in fields such as adsorption and catalysis.
作为一种在凝胶乳液中用作稳定剂的小分子凝胶剂，它具有诸多优点，如用量低、与相比例无关且易于控制。在本研究中，设计并合成了一种胆固醇衍生物（CSA）用作凝胶乳液的稳定剂。凝胶化实验表明，这种小分子能够使包括直链烷烃、甲苯、异戊醇和丙酮在内的多种有机溶剂凝胶化。基于这些凝胶化实验，制备了一系列以水为分散相、与水不混溶的有机溶剂为连续相的凝胶乳液。最后，研究了凝胶剂/水/甲苯体系和凝胶剂/水/环己烷体系的凝胶化行为，探讨了不同体系以及同一体系中不同含水量对凝胶乳液结构和稳定性的影响。研究表明，由凝胶剂/水/甲苯体系制备的凝胶乳液表现出优异的稳定性，这可能归因于该胆固醇衍生物在水/甲苯双相体系中表现出的分子自组装行为。研究结果为将凝胶乳液用作模板制备多孔材料并调节其内部结构提供了依据，最终为这些多孔材料在吸附和催化等领域的应用奠定了坚实基础。
