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以色列孕期感染及其对妊娠结局的影响。

Infection During Pregnancy and Effects on Pregnancy Outcomes in Israel.

作者信息

Shapiro Ben David Shirley, Snitser Olga, Parizade Miriam, Orvieto Noam, Segal Yaacov, Adler Limor

机构信息

Health Division, Maccabi Healthcare Services, Tel Aviv 6812509, Israel.

Family Medicine Department, Faculty of Medical & Health Science, Tel Aviv University, Tel Aviv 6997801, Israel.

出版信息

Microorganisms. 2024 Dec 13;12(12):2572. doi: 10.3390/microorganisms12122572.

Abstract

is a parasite that typically causes self-limited gastroenteritis. Little is known about the course of infection and its impact during pregnancy. This retrospective cohort study conducted in Israel assessed the effects of infection on pregnancy and obstetrical outcomes. The study population included pregnant women with a positive PCR stool test for and a control group of pregnant women with negative tests, matched at a 3:1 ratio based on age, gestational week, and sector. Their medical records were retrieved for symptoms, treatments, pregnancy termination, gestational age, birth weight, Apgar score, and head circumference. Fisher's exact or chi-squared tests were used to determine significance. Between January 2020 and December 2023, 2512 pregnant women underwent PCR stool testing. Of these, 93 were positive for , mostly in 2022. Their median age was 31 (range: 23-42 years), and 77.4% were from medium-high socioeconomic status. The most common symptom was diarrhea (90/93, 96.7%). The infection was self-limiting in all cases, with none requiring specific treatment. No significant differences were found in miscarriage rate, delivery week, birth weight, Apgar score, or head circumference compared to the controls. This study illuminates the clinical course of infection in pregnant women, emphasizing a generally favorable outcome without the necessity for therapeutic intervention.

摘要

是一种通常会引起自限性肠胃炎的寄生虫。关于其感染过程及其在孕期的影响,人们了解甚少。这项在以色列开展的回顾性队列研究评估了[寄生虫名称未给出]感染对妊娠及产科结局的影响。研究人群包括粪便PCR检测呈阳性的孕妇以及检测结果为阴性的孕妇对照组,后者按年龄、孕周和地区以3:1的比例进行匹配。检索了她们的病历以获取症状、治疗情况、妊娠终止情况、孕周、出生体重、阿氏评分和头围等信息。采用Fisher精确检验或卡方检验来确定显著性。在2020年1月至2023年12月期间,2512名孕妇接受了粪便PCR检测。其中,93人[寄生虫名称未给出]检测呈阳性,大多在2022年。她们的中位年龄为31岁(范围:23 - 42岁),77.4%来自中高社会经济地位。最常见的症状是腹泻(90/93,96.7%)。所有病例中的感染均为自限性,无人需要特殊治疗。与对照组相比,在流产率、分娩孕周、出生体重、阿氏评分或头围方面未发现显著差异。这项研究阐明了孕妇感染[寄生虫名称未给出]的临床过程,并强调了总体预后良好,无需进行治疗干预。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbef/11678744/61c1f97e64ee/microorganisms-12-02572-g001.jpg

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