Trenouth M J
Anat Rec. 1985 Feb;211(2):205-12. doi: 10.1002/ar.1092110213.
Asymmetry of the human skull in the frontal and basal views has been described previously as a normal feature in adults. However, no investigation has been performed during the fetal period to see when asymmetry first develops. Previous quantitative methods for measuring asymmetry have relied upon defining anatomical points and using geometrical constructions. In the present study image outlines and their centroids (centers of area) were related to each other via a rectangular coordinate reference grid using the technique of morphanalysis. The centroids were shifted to the left relative to the coordinate reference grid indicating a left side expansion. Also the signed area under the cyclical curve, which is zero for a perfectly symmetrical shape, showed a negative shift indicating asymmetry. The cranium was found to be the major site of asymmetry caused by unequal development of the cerebral hemispheres. The asymmetrical development of the temporal lobes caused a greater displacement of the nasomaxillary segment on the left leading to a rotation of the face on the cranium.
人类颅骨在额面和底面观的不对称性先前已被描述为成年人的一种正常特征。然而，尚未在胎儿期进行调查以观察不对称性首次出现的时间。先前测量不对称性的定量方法依赖于定义解剖学点并使用几何结构。在本研究中，使用形态分析技术，图像轮廓及其质心（面积中心）通过矩形坐标参考网格相互关联。质心相对于坐标参考网格向左移动，表明左侧扩张。此外，对于完美对称形状为零的周期性曲线下的有符号面积显示出负向偏移，表明存在不对称性。发现颅骨是由大脑半球发育不均引起的不对称的主要部位。颞叶的不对称发育导致左侧鼻上颌段的更大移位，从而导致面部在颅骨上的旋转。
