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1
Update on Fatty Acids and the Brain.脂肪酸与大脑的最新进展
Nutrients. 2024 Dec 23;16(24):4416. doi: 10.3390/nu16244416.
2
Changes in fatty acid composition of human brain myelin lipids during maturation.人脑髓磷脂脂质在成熟过程中脂肪酸组成的变化。
J Neurochem. 1978 Jun;30(6):1383-90. doi: 10.1111/j.1471-4159.1978.tb10470.x.
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Lipid and fatty acid composition of myelin purified from normal and MS brains.从正常大脑和多发性硬化症大脑中纯化得到的髓磷脂的脂质和脂肪酸组成。
Eur Neurol. 1973;10(4):250-60. doi: 10.1159/000114281.
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Effect of fatty acid-enriched diet on the composition of fatty acids in lipids of cerebral myelin during development.富含脂肪酸的饮食对发育过程中脑髓磷脂脂质中脂肪酸组成的影响。
Neuropatol Pol. 1985;23(1):119-27.
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[Effect of ethylnitrosourea poisoning on the fatty acid content of myelin lipids].[乙基亚硝基脲中毒对髓磷脂脂质脂肪酸含量的影响]
Neuropatol Pol. 1981 Jan-Mar;19(1):91-106.
7
Biosynthesis of the myelin sheath. In: lipids, malnutrition & the developing brain.髓鞘的生物合成。载于：《脂质、营养不良与发育中的大脑》
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Arch Neurol. 1977 May;34(5):288-94. doi: 10.1001/archneur.1977.00500170042008.
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Types of fatty acids in brain lipids, their derivation and function. In: lipids, malnutrition & the developing brain.脑脂质中的脂肪酸类型、其来源及功能。载于：《脂质、营养不良与发育中的大脑》
Ciba Found Symp. 1971:59-72. doi: 10.1002/9780470719862.ch4.

本文引用的文献

1
Polyunsaturated Fatty Acids: Conversion to Lipid Mediators, Roles in Inflammatory Diseases and Dietary Sources.多不饱和脂肪酸：向脂质介质的转化、在炎症性疾病中的作用和膳食来源。
Int J Mol Sci. 2023 May 16;24(10):8838. doi: 10.3390/ijms24108838.
2
Nutritional supplement induced modulations in the functional connectivity of a porcine brain.营养补充剂对猪脑功能连接的调制作用。
Nutr Neurosci. 2024 Feb;27(2):147-158. doi: 10.1080/1028415X.2023.2166803. Epub 2023 Jan 19.
3
Molecular and Signaling Mechanisms for Docosahexaenoic Acid-Derived Neurodevelopment and Neuroprotection.二十二碳六烯酸衍生的神经发育和神经保护的分子和信号机制。
Int J Mol Sci. 2022 Apr 22;23(9):4635. doi: 10.3390/ijms23094635.
4
Maternal Supply of Both Arachidonic and Docosahexaenoic Acids Is Required for Optimal Neurodevelopment.母体同时提供花生四烯酸和二十二碳六烯酸是最佳神经发育所必需的。
Nutrients. 2021 Jun 16;13(6):2061. doi: 10.3390/nu13062061.
5
Higher n-3 Polyunsaturated Fatty Acid Diet Improves Long-Term Neuropathological and Functional Outcome after Repeated Mild Traumatic Brain Injury.较高的 n-3 多不饱和脂肪酸饮食可改善反复轻度创伤性脑损伤后的长期神经病理学和功能结局。
J Neurotrauma. 2021 Sep 15;38(18):2622-2632. doi: 10.1089/neu.2021.0096. Epub 2021 Jul 20.
6
Docosahexaenoic acid and the brain- what is its role?二十二碳六烯酸与大脑——它有什么作用？
Asia Pac J Clin Nutr. 2019;28(4):675-688. doi: 10.6133/apjcn.201912_28(4).0002.
7
The search for true numbers of neurons and glial cells in the human brain: A review of 150 years of cell counting.探寻人类大脑中神经元和神经胶质细胞的真实数量：150年细胞计数研究综述
J Comp Neurol. 2016 Dec 15;524(18):3865-3895. doi: 10.1002/cne.24040. Epub 2016 Jun 16.
8
Mood-stabilizers target the brain arachidonic acid cascade.心境稳定剂靶向大脑花生四烯酸级联。
Curr Mol Pharmacol. 2009 Jun;2(2):207-14. doi: 10.2174/1874467210902020207.
9
Dietary n-3 PUFA deprivation alters expression of enzymes of the arachidonic and docosahexaenoic acid cascades in rat frontal cortex.膳食中n-3多不饱和脂肪酸缺乏会改变大鼠额叶皮质中花生四烯酸和二十二碳六烯酸级联反应相关酶的表达。
Mol Psychiatry. 2007 Feb;12(2):151-7. doi: 10.1038/sj.mp.4001887. Epub 2006 Sep 19.
10
One generation of n-3 polyunsaturated fatty acid deprivation increases depression and aggression test scores in rats.一代n-3多不饱和脂肪酸缺乏会增加大鼠的抑郁和攻击性测试得分。
J Lipid Res. 2006 Jan;47(1):172-80. doi: 10.1194/jlr.M500362-JLR200. Epub 2005 Oct 6.

脂肪酸与大脑的最新进展

Update on Fatty Acids and the Brain.

作者信息

Sinclair Andrew J

机构信息

Department of Nutrition, Dietetics and Food, School of Clinical Sciences, Monash University, Notting Hill, VIC 3168, Australia.

Faculty of Health, Deakin University, Burwood, VIC 3152, Australia.

出版信息

Nutrients. 2024 Dec 23;16(24):4416. doi: 10.3390/nu16244416.

DOI:10.3390/nu16244416
PMID:39771036
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11678669/
Abstract

The brain is a lipid-rich organ, mainly due to the very high lipid content of myelin, but in addition to this, all the neuronal cell membranes, of which there are over 80 billion in the human brain [...].

摘要

大脑是一个富含脂质的器官，这主要归因于髓磷脂非常高的脂质含量，但除此之外，所有神经元细胞膜（人类大脑中有超过800亿个神经元细胞膜）……