Rathomi Hilmi S, Katzenellenbogen Judith, Mavaddat Nahal, Woods Kirsty, Thompson Sandra C
School of Population and Global Health, University of Western Australia, Crawley, WA 6009, Australia.
Faculty of Medicine, Universitas Islam Bandung, Bandung 40116, Indonesia.
Nutrients. 2024 Dec 23;16(24):4426. doi: 10.3390/nu16244426.
Time-restricted eating (TRE) shows promise for managing weight and metabolic issues, yet its application in real-world healthcare settings remains underexplored. This study aims to assess the real-world utilisation and short-term outcomes of TRE in clinical practice.
This observational study used a retrospective chart review of 271 adults who attended a metabolic specialist clinic between 2019 and 2023. Descriptive statistics and multivariable logistic regression were used to identify factors associated with TRE adoption, while paired sample -tests evaluated changes in outcomes among those who received TRE advice.
Among the 271 patients, 76% were female, 90% Caucasian, and 94% overweight/obese. Of all patients, 47.2% received TRE advice, mainly using the 16:8 method, alongside additional dietary guidance for 60% of patients. Working status and baseline metabolic profiles were the only factors significantly associated with TRE adoption. Among those who followed TRE, 81% experienced modest but significant reductions in weight (-1.2 kg, < 0.01), BMI (-0.4 kg/m, < 0.01), and waist circumference (-3.7 cm, < 0.01).
This study highlights TRE as a feasible and practical dietary strategy for improving metabolic health in healthcare settings. However, further research and improved data capture are needed to explore long-term adherence, potential adverse effects, and the effectiveness of TRE across diverse patient populations.
限时进食(TRE)在控制体重和代谢问题方面显示出前景,但在现实世界的医疗环境中的应用仍未得到充分探索。本研究旨在评估TRE在临床实践中的实际应用情况和短期结果。
这项观察性研究对2019年至2023年间到代谢专科门诊就诊的271名成年人进行了回顾性病历审查。使用描述性统计和多变量逻辑回归来确定与采用TRE相关的因素,同时配对样本检验评估接受TRE建议者的结果变化。
在271名患者中,76%为女性,90%为白种人,94%超重/肥胖。在所有患者中,47.2%接受了TRE建议,主要采用16:8方法,60%的患者还接受了额外的饮食指导。工作状态和基线代谢状况是与采用TRE显著相关的唯一因素。在遵循TRE的患者中,81%的人体重(-1.2千克,<0.01)、体重指数(-0.4千克/米,<0.01)和腰围(-3.7厘米,<0.01)有适度但显著的下降。
本研究强调TRE是一种在医疗环境中改善代谢健康的可行且实用的饮食策略。然而,需要进一步研究并改进数据收集,以探索长期依从性、潜在不良反应以及TRE在不同患者群体中的有效性。