Wu Yitian, Shi Yewen, Gu Tianmin, Du Xiushuai, Du Zhiyuan, Zhang Chi, Sun Ke, Zhang Yue, Guo Xiaojing, Wang Shenghan, Zheng Weiwei, He Yi, Liu Wei
Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China.
Key Laboratory of the Public Health Safety, Ministry of Education, Department of Environmental Health, School of Public Health, Fudan University, Shanghai 200032, China.
Toxics. 2024 Nov 24;12(12):844. doi: 10.3390/toxics12120844.
Non-targeted screening (NTS) technology has been showing significant potential in identifying contaminants of emerging concern (CECs) in water and has attracted great attention in academia in recent years. It is a method that analyzes samples without pre-selecting substances, enabling the detection and identification of unknown compounds, which is crucial for environmental health and public protection. This study uses the Bibliometrix package in R 4.4.1 and CiteSpace 6.3.R1 software to statistically analyze 589 relevant publications from the Web of Science Core Collection from 2007 to 2024. Our work concentrates on NTS of water bodies; thus, articles that only analyze water sediments without analyzing the water were not considered for inclusion. By conducting a quantitative analysis and visualizing the publication trends, countries, authors, journals, and keywords, the present study identifies research hotspots, compositions, and paradigms within this field, trying to analyze the horizontal and vertical development trends and structural evolution of the research area. The research found that the application of NTS in water pollution studies has progressed through three phases: theoretical exploration, rapid development, and steady progress. From the national level, China leads with the highest number of publications (131), followed by Germany (105), Spain (50), and the United States (39). The top three authors by publication volume are J. Hollender, Nikolaos S. Thomaidis, and Emma L. Schymanski, while the top three by citation count are J. Hollender, Emma L. Schymanski, and M. Krauss. However, international collaboration between countries and researchers still remains an area for improvement. Science of the Total Environment is the journal with the highest number of publications (81), and Environmental Science & Technology holds the highest number of citations. Research on NTS methodologies, suspect screening, and health risk assessments are hot topics in the academic community. Future research is expected to be multidisciplinary, with emerging hotspots likely to focus on including the identification of novel pollutants through NTS, toxicity assessments of biotransformed compounds, and the health impacts and mechanisms of related compounds.
非靶向筛查（NTS）技术在识别水中新兴关注污染物（CECs）方面已显示出巨大潜力，近年来在学术界备受关注。它是一种在不预先选择物质的情况下分析样品的方法，能够检测和识别未知化合物，这对环境健康和公众保护至关重要。本研究使用R 4.4.1中的Bibliometrix包和CiteSpace 6.3.R1软件，对2007年至2024年Web of Science核心合集中的589篇相关出版物进行统计分析。我们的工作集中在水体的非靶向筛查；因此，仅分析水沉积物而不分析水体的文章不被纳入考虑。通过进行定量分析并可视化出版趋势、国家、作者、期刊和关键词，本研究确定了该领域的研究热点、组成和范式，试图分析该研究领域的横向和纵向发展趋势以及结构演变。研究发现，NTS在水污染研究中的应用经历了三个阶段：理论探索、快速发展和稳步推进。从国家层面来看，中国以最高的出版物数量（131篇）领先，其次是德国（105篇）、西班牙（50篇）和美国（39篇）。按出版物数量排名前三的作者是J. Hollender、Nikolaos S. Thomaidis和Emma L. Schymanski，而按被引次数排名前三的是J. Hollender、Emma L. Schymanski和M. Krauss。然而，国家和研究人员之间的国际合作仍有改进空间。《总体环境科学》是出版物数量最多的期刊（81篇），《环境科学与技术》的被引次数最高。关于NTS方法、可疑筛查和健康风险评估的研究是学术界的热门话题。未来的研究预计将是多学科的，新兴热点可能集中在通过NTS识别新型污染物、生物转化化合物的毒性评估以及相关化合物的健康影响和作用机制等方面。
