关于“mRNA治疗与基因递送的最新进展”特刊的社论
Editorial on Special Issue "State-of-Art in mRNA Therapeutics and Gene Delivery".
作者信息
Mendonça Liliana S
机构信息
Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Center for Innovative Biomedicine and Biotechnology, University of Coimbra, 3004-504 Coimbra, Portugal.
出版信息
Pharmaceutics. 2024 Dec 13;16(12):1590. doi: 10.3390/pharmaceutics16121590.
Abstract
RNA therapeutics are a class of medicines based on the insertion of a specific genetic message (mRNA) into the cells and the silencing or gene editing of a specific mRNA [...].
摘要
RNA疗法是一类基于将特定遗传信息（mRNA）导入细胞以及使特定mRNA沉默或进行基因编辑的药物[……]。
相似文献
1
Editorial on Special Issue "State-of-Art in mRNA Therapeutics and Gene Delivery".关于“mRNA治疗与基因递送的最新进展”特刊的社论
Pharmaceutics. 2024 Dec 13;16(12):1590. doi: 10.3390/pharmaceutics16121590.
2
Lipid Nanoparticle Technology for Clinical Translation of siRNA Therapeutics.脂质纳米颗粒技术在 siRNA 治疗药物临床转化中的应用
Acc Chem Res. 2019 Sep 17;52(9):2435-2444. doi: 10.1021/acs.accounts.9b00368. Epub 2019 Aug 9.
3
Gene editing therapeutics based on mRNA delivery.基于 mRNA 递送的基因编辑治疗学。
Adv Drug Deliv Rev. 2023 Sep;200:115026. doi: 10.1016/j.addr.2023.115026. Epub 2023 Jul 27.
4
Nanoscale delivery platforms for RNA therapeutics: Challenges and the current state of the art.用于 RNA 治疗的纳米递药平台：挑战和当前的技术现状。
Med. 2022 Mar 11;3(3):167-187. doi: 10.1016/j.medj.2022.02.001.
5
mRNA delivery via non-viral carriers for biomedical applications.通过非病毒载体进行的mRNA递送在生物医学中的应用。
Int J Pharm. 2021 Sep 25;607:121020. doi: 10.1016/j.ijpharm.2021.121020. Epub 2021 Aug 17.
6
Cell-Selective Messenger RNA Delivery and CRISPR/Cas9 Genome Editing by Modulating the Interface of Phenylboronic Acid-Derived Lipid Nanoparticles and Cellular Surface Sialic Acid.通过调节苯硼酸衍生脂质纳米颗粒与细胞表面唾液酸的界面实现细胞选择性信使 RNA 传递和 CRISPR/Cas9 基因组编辑。
ACS Appl Mater Interfaces. 2019 Dec 18;11(50):46585-46590. doi: 10.1021/acsami.9b17749. Epub 2019 Dec 9.
7
Biomedical applications of mRNA nanomedicine.信使核糖核酸纳米药物的生物医学应用。
Nano Res. 2018 Oct;11(10):5281-5309. doi: 10.1007/s12274-018-2146-1. Epub 2018 Jul 27.
8
Insight into RNA-based Therapies for Ovarian Cancer.基于 RNA 的卵巢癌治疗的新视角。
Curr Pharm Des. 2023;29(34):2692-2701. doi: 10.2174/0113816128270476231023052228.
9
Advances in the delivery of RNA therapeutics: from concept to clinical reality.RNA疗法的递送进展：从概念到临床实践
Genome Med. 2017 Jun 27;9(1):60. doi: 10.1186/s13073-017-0450-0.
10
RNA-based medicine: from molecular mechanisms to therapy.基于 RNA 的药物：从分子机制到治疗。
EMBO J. 2023 Nov 2;42(21):e114760. doi: 10.15252/embj.2023114760. Epub 2023 Sep 20.
本文引用的文献
1
Development of Biolayer Interferometry (BLI)-Based Double-Stranded RNA Detection Method with Application in mRNA-Based Therapeutics and Vaccines.基于生物层干涉术（BLI）的双链RNA检测方法的开发及其在基于mRNA的治疗药物和疫苗中的应用
Pharmaceutics. 2024 Sep 19;16(9):1227. doi: 10.3390/pharmaceutics16091227.
2
Nanoparticle-Mediated Therapy with miR-198 Sensitizes Pancreatic Cancer to Gemcitabine Treatment through Downregulation of VCP-Mediated Autophagy.纳米颗粒介导的miR-198疗法通过下调VCP介导的自噬使胰腺癌对吉西他滨治疗敏感。
Pharmaceutics. 2023 Jul 28;15(8):2038. doi: 10.3390/pharmaceutics15082038.
3
Crotamine/siRNA Nanocomplexes for Functional Downregulation of Syndecan-1 in Renal Proximal Tubular Epithelial Cells.用于肾近端小管上皮细胞中Syndecan-1功能下调的巴曲酶/小干扰RNA纳米复合物
Pharmaceutics. 2023 May 23;15(6):1576. doi: 10.3390/pharmaceutics15061576.
4
Platelet Activation by Antisense Oligonucleotides (ASOs) in the Göttingen Minipig, including an Evaluation of Glycoprotein VI (GPVI) and Platelet Factor 4 (PF4) Ontogeny.反义寡核苷酸（ASOs）对哥廷根小型猪血小板的激活作用，包括糖蛋白VI（GPVI）和血小板因子4（PF4）个体发育的评估。
Pharmaceutics. 2023 Mar 31;15(4):1112. doi: 10.3390/pharmaceutics15041112.
5
DLin-MC3-Containing mRNA Lipid Nanoparticles Induce an Antibody Th2-Biased Immune Response Polarization in a Delivery Route-Dependent Manner in Mice.含DLin-MC3的信使核糖核酸脂质纳米颗粒在小鼠体内以依赖递送途径的方式诱导抗体Th2偏向性免疫反应极化。
Pharmaceutics. 2023 Mar 21;15(3):1009. doi: 10.3390/pharmaceutics15031009.
6
Autologous Genetically Enriched Leucoconcentrate in the Preventive and Acute Phases of Stroke Treatment in a Mini-Pig Model.小型猪模型中自体基因富集白细胞浓缩液在中风治疗预防和急性期的应用
Pharmaceutics. 2022 Oct 17;14(10):2209. doi: 10.3390/pharmaceutics14102209.
Zotero 插件