Kitro Amornphat, Sirikul Wachiranun, Polpitakchai Chanachai, Panumasvivat Jinjuta, Yamsiri Ranchana, Tasena Pacharee, Punyaphab Chutima, Rungsiyakull Chaiy, Sapbamrer Ratana, Siviroj Penprapa, Srithanaviboonchai Kriengkrai
Department of Community Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
Environmental and Occupational Medicine Excellence Center, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
Vaccines (Basel). 2024 Dec 7;12(12):1381. doi: 10.3390/vaccines12121381.
The emergence of new COVID-19 variants continues to affect healthcare workers (HCWs) and vulnerable populations in the post-pandemic era. This study aims to assess the willingness, perceptions, and factors associated with booster COVID-19 vaccine uptake in this context.
A cross-sectional study was conducted between October 2023 and May 2024 among Thai adults (>20 years old) in Chiang Mai, Northern Thailand. Participants included HCWs and patients with chronic medical conditions. People who had received a monovalent XBB-derived booster vaccine were excluded.
Data related to a total of 811 participants were analyzed, with 328 from the vulnerable group and 483 HCWs. Willingness to receive the booster was similar in both groups (43.3% in HCWs, 45.0% in the vulnerable group). Low-risk perception (59.6%-83.5%), minimal impact on daily life (60.4%-62.9%), and doubts about booster efficacy (75.9%-81.4%) were prevalent negative thoughts toward the booster. Having received a flu vaccine (aOR 2.1), concerns about the impact on life of COVID-19 (aOR 1.8), and beliefs in booster safety (aOR 1.8) and vaccine effectiveness against severe disease (aOR 2.7) were associated with increased willingness.
Only 44% of participants were willing to receive a COVID-19 booster. Policymakers can use these insights to develop strategies to increase vaccine uptake in the post-pandemic era.
新型冠状病毒病（COVID-19）变体的出现继续影响着大流行后时代的医护人员（HCWs）和弱势群体。本研究旨在评估在这种情况下接种COVID-19加强疫苗的意愿、认知及相关因素。
2023年10月至2024年5月期间，在泰国北部清迈对泰国成年人（>20岁）进行了一项横断面研究。参与者包括医护人员和患有慢性疾病的患者。已接种单价XBB衍生加强疫苗的人员被排除在外。
共分析了811名参与者的数据，其中弱势群体328名，医护人员483名。两组接受加强疫苗接种的意愿相似（医护人员中为43.3%，弱势群体中为45.0%）。对加强疫苗的低风险认知（59.6%-83.5%）、对日常生活影响最小（60.4%-62.9%）以及对加强疫苗效力的怀疑（75.9%-81.4%）是对加强疫苗普遍存在的负面想法。接种过流感疫苗（调整优势比[aOR]为2.1）、对COVID-19对生活影响的担忧（aOR为1.8）以及对加强疫苗安全性的信念（aOR为1.8）和疫苗对重症疾病的有效性（aOR为2.7）与意愿增加相关。
只有44%的参与者愿意接种COVID-19加强疫苗。政策制定者可利用这些见解制定策略，以提高大流行后时代的疫苗接种率。
