Kahn Anna-Lea, Spasenoska Dijana, Ekra Kouadio Daniel, Coulibaly Soplé Ruth, Yao Kossia, Kouadio Sié Kabran, Sar Aminatou, Robertson Joanie
World Health Organization (WHO) Headquarters, Avenue Appia 20, 1211 Geneva, Switzerland.
Swiss Centre for International Health, Swiss Tropical and Public Health Institute, 4123 Basel, Switzerland.
Vaccines (Basel). 2024 Dec 16;12(12):1414. doi: 10.3390/vaccines12121414.
Persistent inequities in access to vaccinations pose challenges for immunization programs worldwide. Innovations facilitating vaccine delivery, such as leveraging vaccine thermostability through a Controlled Temperature Chain (CTC), have emerged as a potential solution to increase coverage in low- and middle-income countries (LMICs) countries such as Côte d'Ivoire, reducing dependence on the cold chain and improving vaccine delivery efficiency. However, the added value of thermostable vaccines and their integration into national immunization programs is under-recognized by stakeholders. This consultation aimed to convene key immunization stakeholders in Côte d'Ivoire in order to examine their perceptions regarding the value of vaccine thermostability to address barriers to outreach and equity in immunization programs.
A novel workshop model involving structured group discussions was used to document the viewpoints of national stakeholders representing different areas of the immunization program. They prioritized barriers undermining coverage and equity in their country and explored the potential impact of CTC on the immunization program in the context of thermostable vaccines. The vaccines discussed were for Hepatitis B, Human Papillomavirus, and Meningitis.
The workshop outcomes highlighted the context and vaccine-specific variation of the importance of certain barriers, emphasizing the need for tailored strategies. The barriers considered most likely to be alleviated by vaccine thermostability were under the categories of human resource management, vaccine supply and logistics, and services delivery. The least relevant category of barriers concerned demand generation.
The consultation provided valuable insights into stakeholder perspectives, priorities, and conditions for the effective integration of thermostable vaccines, informing future product development and policy decisions to optimize vaccine delivery and address immunization challenges in LMICs.
全球免疫规划面临着疫苗接种可及性方面持续存在的不平等问题。诸如通过温控冷链(CTC)利用疫苗热稳定性等促进疫苗交付的创新方法,已成为提高低收入和中等收入国家(如科特迪瓦)疫苗接种覆盖率的潜在解决方案,可减少对冷链的依赖并提高疫苗交付效率。然而,热稳定疫苗的附加价值及其纳入国家免疫规划的情况,尚未得到利益相关者的充分认识。本次磋商会旨在召集科特迪瓦关键的免疫相关利益相关者,以了解他们对疫苗热稳定性在应对免疫规划中的推广障碍和公平性方面价值的看法。
采用一种涉及结构化小组讨论的新型研讨会模式,记录代表免疫规划不同领域的国家利益相关者的观点。他们对本国影响覆盖率和公平性的障碍进行了优先排序,并探讨了在热稳定疫苗背景下温控冷链对免疫规划的潜在影响。所讨论的疫苗包括乙型肝炎、人乳头瘤病毒和脑膜炎疫苗。
研讨会成果突出了某些障碍重要性的具体情况和疫苗特异性差异,强调需要制定针对性策略。最有可能因疫苗热稳定性而得到缓解的障碍类别包括人力资源管理、疫苗供应与物流以及服务提供。最不相关的障碍类别涉及需求产生。
本次磋商会为利益相关者的观点、优先事项以及热稳定疫苗有效整合的条件提供了宝贵见解,为未来的产品开发和政策决策提供了参考,以优化疫苗交付并应对低收入和中等收入国家的免疫挑战。