Chen Chen, Reeves Mathew J, Lisabeth Lynda D
Department of Epidemiology, University of Michigan, Ann Arbor (C.C., L.D.L.).
Department of Epidemiology, Michigan State University, East Lansing (M.J.R.).
Stroke. 2025 Feb;56(2):265-275. doi: 10.1161/STROKEAHA.124.048773. Epub 2024 Dec 30.
Women experience more poststroke physical activity limitations, but sex differences in social activity participation, an important patient-reported outcome for stroke recovery, remain uncertain.
Incident stroke survivors aged ≥65 years were identified from the US NHATS (National Health and Aging Trends Study), 2011-2022. Participants were asked to report restricted participation in the past month in 2 formal activities (religious services and clubs/classes) and 2 informal activities (visiting friends/family and going out for enjoyment) in the year of stroke onset. Logistic regression was used to assess sex differences in any participation restrictions across the 4 activities and within each activity, without and with adjustment for potential confounders, including sociodemographic, social-environmental, technological- and service environmental, psychological, health condition-related factors, and activity limitations.
Among stroke survivors (N=469; 56.6% women; 50.4% of 75-84 years of age), women were more likely to be older, widowed, live alone, not currently driving, have worse physical capacity, and have more activity limitations. Women had a higher unadjusted prevalence of any participation restriction (40.3% versus 29.4%; odds ratio, 1.90 [95% CI, 1.21-2.99]) and restriction in attending religious services (27.5% versus 19.0%; odds ratio, 1.80 [95% CI, 1.08-3.02]). These sex differences were attenuated most after individual adjustment for physical capacity, marital status, and driving mobility, followed by adjustment for comorbidities, living alone, and activity limitations. No significant sex differences were found after simultaneously adjusting for these factors (adjusted odds ratio, 1.36 [95% CI, 0.70-2.65] for any participation restrictions; adjusted odds ratio, 1.36 [95% CI, 0.74-2.49] for restrictions in religious service attendance).
Social participation restrictions are prevalent among older stroke survivors, particularly for women, which appears to be attributable to sex differences in social factors and prestroke health. Future interventions targeting vulnerable subgroups, including socially isolated women and women with poorer health, should be considered.
女性中风后身体活动受限的情况更为常见,但社会活动参与方面的性别差异(中风恢复的一项重要患者报告结局)仍不明确。
从2011年至2022年的美国国家健康与老龄化趋势研究(NHATS)中确定年龄≥65岁的首次中风幸存者。参与者被要求报告在中风发病当年过去一个月内参与2项正式活动(宗教活动和俱乐部/课程)和2项非正式活动(拜访朋友/家人和外出娱乐)受到限制的情况。采用逻辑回归分析评估在这4项活动以及每项活动中参与受限情况的性别差异,未调整以及调整了潜在混杂因素,包括社会人口学、社会环境、技术和服务环境、心理、健康状况相关因素以及活动受限情况。
在中风幸存者中(N = 469;56.6%为女性;75 - 84岁的占50.4%),女性更可能年龄较大、丧偶、独居、目前不开车、身体能力较差且活动受限更多。女性在任何参与受限方面未经调整的患病率更高(40.3%对29.4%;比值比,1.90[95%CI,1.21 - 2.99]),在参加宗教活动受限方面也是如此(27.5%对19.0%;比值比,1.80[95%CI,1.08 - 3.02])。在对身体能力、婚姻状况和驾驶能力进行个体调整后,这些性别差异大部分减弱,其次是对合并症、独居和活动受限进行调整。在同时调整这些因素后未发现显著的性别差异(任何参与受限的调整后比值比,1.36[95%CI = 0.70 - 2.65];参加宗教活动受限的调整后比值比,1.36[95%CI,0.74 - 2.49])。
社会参与受限在老年中风幸存者中普遍存在,尤其是女性,这似乎归因于社会因素和中风前健康状况的性别差异。应考虑针对包括社会孤立的女性和健康状况较差的女性在内的弱势群体的未来干预措施。