Bouvet A, Acar J F
Ann Cardiol Angeiol (Paris). 1985 Jan;34(1):1-3.
Prevention of bacterial endocarditis is aimed at limiting the frequency, size, and duration of transient bacteremia with subsequent bacterial implantation on valvular endothelium in patients with cardiopathy. Any procedure involving mucosa rich in normal flora or an infectious site can result in bacteremia, which can be minimized by selecting diagnostic and therapeutic procedures which are least traumatic. In addition, proper antibiotic prophylaxis should be administered according to the most frequently encountered bacteria: Streptococcus viridans during dental manipulations, enterococci during urogenital or intestinal procedures, and staphylococcal species from skin lacerations or cardiac surgery. The different antibiotic prophylactic regimens suggested at the present time vary according to the patient and the particular circumstances surrounding his illness. These regimens should be modified according to future epidemiologic findings in bacterial endocarditis.
预防细菌性心内膜炎旨在限制暂时性菌血症的频率、规模和持续时间,随后防止细菌植入心脏病患者的瓣膜内皮。任何涉及富含正常菌群的黏膜或感染部位的操作都可能导致菌血症,通过选择创伤最小的诊断和治疗程序可将其降至最低。此外,应根据最常遇到的细菌给予适当的抗生素预防:牙科操作时针对草绿色链球菌,泌尿生殖系统或肠道操作时针对肠球菌,皮肤撕裂伤或心脏手术时针对葡萄球菌属。目前建议的不同抗生素预防方案因患者及其病情的具体情况而异。这些方案应根据细菌性心内膜炎未来的流行病学研究结果进行调整。