Bansal Kshitij, Chawla Tanushree, Goyal Chanchal, Goyal Vinay
Medanta, The Medicity, Gurugram, India.
ICMR, New Delhi, India.
Am J Trop Med Hyg. 2025 Jan 7;112(4):916-917. doi: 10.4269/ajtmh.24-0359. Print 2025 Apr 2.
This report presents a rare case of acute transverse myelitis (ATM) after mumps infection in a 33-year-old male. Symptoms included fever, parotid and scrotal swelling, and subsequent sensory-motor paraparesis. Magnetic resonance imaging revealed long-segment spinal cord hyperintensity, and cerebrospinal fluid analysis showed pleocytosis and elevated protein, with positive mumps virus antibodies. Treatment with high-dose pulse steroids resulted in significant improvement. This underscores the association between mumps and ATM in adults, suggesting an autoimmune-inflammatory mechanism. The favorable response to steroid therapy emphasizes its efficacy in managing mumps-associated ATM. Recognizing such neurological complications is crucial for prompt diagnosis and appropriate intervention.
本报告介绍了一例罕见的33岁男性腮腺炎感染后急性横贯性脊髓炎(ATM)病例。症状包括发热、腮腺和阴囊肿胀,以及随后出现的感觉运动性双下肢轻瘫。磁共振成像显示长节段脊髓高信号,脑脊液分析显示细胞增多和蛋白升高,腮腺炎病毒抗体呈阳性。大剂量脉冲类固醇治疗后有显著改善。这突出了成人腮腺炎与ATM之间的关联,提示存在自身免疫炎症机制。对类固醇治疗的良好反应强调了其在治疗腮腺炎相关ATM方面的疗效。认识到这种神经并发症对于及时诊断和适当干预至关重要。