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小肠肉瘤样癌

Sarcomatoid carcinoma of small intestine.

作者信息

Hoseini Sayed Shahabuddin, Tang Xiaoyu, Dewar Rajan

机构信息

Pathology, Westchester Medical Center, Valhalla, New York, USA.

Department of Pathology, New York Medical College, Valhalla, New York, USA.

出版信息

BMJ Case Rep. 2025 Jan 7;18(1):e261160. doi: 10.1136/bcr-2024-261160.

DOI:10.1136/bcr-2024-261160
PMID:39773955
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11751603/
Abstract

Sarcomatoid carcinoma is a rare type of tumour consisting of neoplastic cells expressing both epithelial and mesenchymal cell markers. The small intestine is a rare site for sarcomatoid carcinoma and to date, a few cases have been reported. In this manuscript, a case of jejunal sarcomatoid carcinoma in a man in his 50s is reported. A review of the literature on sarcomatoid carcinomas of small bowel is presented.

摘要

肉瘤样癌是一种罕见的肿瘤类型,由表达上皮和间充质细胞标志物的肿瘤细胞组成。小肠是肉瘤样癌的罕见发生部位,迄今为止,仅有少数病例报道。在本论文中,报告了一例50多岁男性的空肠肉瘤样癌病例。并对小肠肉瘤样癌的文献进行了综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac14/11751603/547bc23d3dcb/bcr-18-1-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac14/11751603/60c3120caa63/bcr-18-1-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac14/11751603/67b30c334c57/bcr-18-1-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac14/11751603/547bc23d3dcb/bcr-18-1-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac14/11751603/60c3120caa63/bcr-18-1-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac14/11751603/67b30c334c57/bcr-18-1-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac14/11751603/547bc23d3dcb/bcr-18-1-g003.jpg

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BMJ Case Rep. 2025 Jan 7;18(1):e261160. doi: 10.1136/bcr-2024-261160.
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本文引用的文献

1
Comprehensive genomic profiling of small bowel adenocarcinoma by tissue and plasma biopsy.小肠腺癌的组织和血浆活检的全面基因组分析。
Genomics. 2024 Jan;116(1):110766. doi: 10.1016/j.ygeno.2023.110766. Epub 2023 Dec 21.
2
A rare multiple primary sarcomatoid carcinoma (SCA) of small intestine harboring driver gene mutations: a case report and a literature review.一例罕见的携带驱动基因突变的小肠多原发性肉瘤样癌(SCA):病例报告及文献综述
Transl Cancer Res. 2021 Feb;10(2):1150-1161. doi: 10.21037/tcr-20-2829.
3
Uterine carcinosarcoma: An overview.
子宫癌肉瘤:概述。
Crit Rev Oncol Hematol. 2021 Jul;163:103369. doi: 10.1016/j.critrevonc.2021.103369. Epub 2021 May 27.
4
Tumor Mutation Burden and Cancer Treatment.肿瘤突变负荷与癌症治疗
JAMA Oncol. 2021 Feb 1;7(2):316. doi: 10.1001/jamaoncol.2020.6371.
5
Sarcomatoid renal cell carcinoma: biology, natural history and management.肉瘤样肾细胞癌:生物学、自然史与治疗。
Nat Rev Urol. 2020 Dec;17(12):659-678. doi: 10.1038/s41585-020-00382-9. Epub 2020 Oct 13.
6
Sarcomatoid Carcinoma of the Lung Presenting as Localized Bronchiectasis: A Case Report and Review of Literature.表现为局限性支气管扩张的肺肉瘤样癌:一例报告并文献复习
Respir Med Case Rep. 2018 May 17;24:143-146. doi: 10.1016/j.rmcr.2018.05.016. eCollection 2018.
7
Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden.对10万个人类癌症基因组的分析揭示了肿瘤突变负荷的全貌。
Genome Med. 2017 Apr 19;9(1):34. doi: 10.1186/s13073-017-0424-2.
8
Diagnosing sarcomatoid carcinoma and carcinosarcoma of the large bowel: heads or tails?诊断大肠肉瘤样癌和癌肉瘤:何去何从?
Int J Surg Pathol. 2015 Feb;23(1):92-3. doi: 10.1177/1066896914542126. Epub 2014 Jul 7.
9
Malignant biphasic tumors of the lungs.肺部恶性双相型肿瘤。
Adv Anat Pathol. 2011 May;18(3):179-89. doi: 10.1097/PAP.0b013e318216980c.
10
Severe anemia inducing preshock caused by sarcomatoid carcinoma of the small intestine.小肠肉瘤样癌导致严重贫血引发休克前期。
Int Surg. 2009 Apr-Jun;94(2):164-70.