Russell I J, Walsh R A
Ann Rheum Dis. 1985 Mar;44(3):151-4. doi: 10.1136/ard.44.3.151.
Two young adults with impending gangrene due to persistent Raynaud's vasospasm were studied by sequential intra-arterial (IA) infusion of three vasodilatory drugs while arterial pressure and plethysmographic digital pulse volume were continuously monitored. The results of the IA infusion accurately predicted relief from vasospastic symptoms by oral drugs of the same class. This method may be useful in selecting the most effective vasodilator for patients with severe vasospasm.
对两名因持续性雷诺血管痉挛而濒临坏疽的年轻成年人进行了研究,通过依次动脉内(IA)输注三种血管扩张药物,同时持续监测动脉压和体积描记法测量的数字脉搏容积。IA输注的结果准确预测了同一类口服药物对血管痉挛症状的缓解情况。这种方法可能有助于为严重血管痉挛患者选择最有效的血管扩张剂。