Silander T, Thor K
Ann Surg. 1985 Mar;201(3):323-7. doi: 10.1097/00000658-198503000-00012.
In patients with obstructive jaundice, biliary decompression can be achieved by an endoprosthesis inserted by a percutaneous transhepatic approach. The prosthesis sometimes becomes dislodged and thus additional percutaneous transhepatic procedures may be required. To avoid this problem, a nondislodgeable endoprosthesis has been developed. The prosthesis is constructed with a layer of biocompatible material (hydrogel) on its surface. The hydrogel is located in grooves around the endoprosthesis and has the ability to absorb liquid, which increases its size. By placing the rings of hydrogel on either side of the obstruction, dislodgement of the prosthesis can be prevented. The nondislodgeable endoprosthesis has been inserted into 11 patients with biliary obstructions due to malignant strictures. No dislodgement has occurred and the established internal drainage reduced serum bilirubin levels without any major complications.
在梗阻性黄疸患者中，可通过经皮经肝途径插入的内支架实现胆道减压。该支架有时会移位，因此可能需要额外的经皮经肝操作。为避免此问题，已开发出一种不易移位的内支架。该支架表面构建有一层生物相容性材料（水凝胶）。水凝胶位于内支架周围的凹槽中，具有吸收液体的能力，这会使其尺寸增大。通过将水凝胶环放置在梗阻两侧，可防止支架移位。已将这种不易移位的内支架插入11例因恶性狭窄导致胆道梗阻的患者体内。未发生移位，已建立的内引流降低了血清胆红素水平，且无任何重大并发症。
