18F-FDG PET/CT描述的嗜酸性粒细胞性心肌炎罕见病例

A Rare Case of Eosinophilic Myocarditis Described With 18F-FDG PET/CT.

作者信息

Peslier Hugo, Metrard Gilles, Malmare Bianca-Angela, Bailly Matthieu

机构信息

From the Nuclear Medicine Department, CHU Orleans, Orleans, France.

Cardiology Department, CHU Orleans, Orleans, France.

出版信息

Clin Nucl Med. 2024 Nov 19. doi: 10.1097/RLU.0000000000005594.

DOI:10.1097/RLU.0000000000005594

PMID:39774516

Abstract

Late-stage eosinophilic myocarditis (or Löffler endocarditis) is known to occur in patients with hypereosinophilic syndrome and can cause restrictive cardiomyopathy. Eosinophilic myocarditis is an acute life-threatening inflammatory disease of the heart that can be associated with cancer. We report a case of a 70-year-old White woman, previously treated for diffuse large B-cell lymphoma in remission, admitted for acute dyspnea with a 1-year history of hypereosinophilia. 18F-FDG PET/CT revealed endocardial uptake consistent with MRI gadolinium enhancement, suggesting left ventricular wall inflammation.

摘要

晚期嗜酸性粒细胞性心肌炎（或吕弗勒心内膜炎）已知发生于高嗜酸性粒细胞综合征患者，并可导致限制性心肌病。嗜酸性粒细胞性心肌炎是一种急性危及生命的心脏炎症性疾病，可能与癌症有关。我们报告一例70岁白人女性病例，该患者曾接受弥漫性大B细胞淋巴瘤治疗且病情缓解，因急性呼吸困难入院，有1年的嗜酸性粒细胞增多病史。18F-FDG PET/CT显示心内膜摄取与MRI钆增强一致，提示左心室壁炎症。