Innovations in Targeting the V2 Receptor.
作者信息
Trepiccione Francesco, Iervolino Anna
机构信息
Department of Medical Translational Sciences, University of Campania "Luigi Vanvitelli," Naples, Italy; and Biology and Molecular Genetics Institute, Biogem, Ariano Irpino, Italy.
出版信息
J Am Soc Nephrol. 2025 Feb 1;36(2):163-165. doi: 10.1681/ASN.0000000601. Epub 2025 Jan 7.
Abstract
摘要
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Characterization of five novel vasopressin V2 receptor mutants causing nephrogenic diabetes insipidus reveals a role of tolvaptan for M272R-V2R mutation.鉴定五种导致肾性尿崩症的新型血管加压素 V2 受体突变体，揭示托伐普坦治疗 M272R-V2R 突变的作用。
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