Horsbøl Trine A, Saltbæk Lena, Urhammer Caroline, Karlsen Randi V, Johansen Christoffer, Bidstrup Pernille E, Høeg Beverley L, Zoffmann Vibeke, Belmonte Federica, Andersen Ingelise, Friberg Anne S, Svendsen Mads N, Christensen Helle G, Glavicic Vesna, Nielsen Dorte L, Dalton Susanne O
National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark; Cancer Survivorship, Danish Cancer Institute, Copenhagen, Denmark.
Cancer Survivorship, Danish Cancer Institute, Copenhagen, Denmark; Department of Clinical Oncology and Palliative Care, Zealand University Hospital, Denmark.
Acta Oncol. 2025 Jan 8;64:34-39. doi: 10.2340/1651-226X.2025.42221.
We previously demonstrated positive effects on quality of life and mental health following breast cancer when comparing a nurse-led follow-up program without scheduled visits (MyHealth) to regular follow-up. This study aims to examine whether MyHealth also positively impacts self-reported work ability.
PATIENTS/MATERIAL AND METHODS: A total of 288 patients, potentially active on the labour market, were randomized to MyHealth or control follow-up after primary treatment for early-stage breast cancer (2017-2019). MyHealth included individual self-management sessions, electronic symptom monitoring, and assistance with navigating healthcare services. Control follow-up consisted of biannual outpatient visits with a physician. Linear mixed-effect models were applied to evaluate the effect of MyHealth on self-reported work ability at 6, 12, 24, and 36 months after randomization as measured by the Work Ability Score (WAS).
Work ability increased significantly in both groups during the first 6 months (mean WAS increase MyHealth: 1.64, 95% confidence interval [CI]: 1.26; 2.02 and control: 1.57, 95% CI: 1.17; 1.97) and continued to increase slightly but non-significantly (p-values > 0.13) until end of follow-up at 36 months. Improvement was especially pronounced among patients reporting poor work ability at baseline. Differences in mean WAS between patients in MyHealth and control follow-up were non-significant and close to zero at all time points (-0.21 to 0.48).
The MyHealth follow-up program had no additional effect on self-reported work ability compared to regular follow-up. Future interventions should target patients with poor work ability and include components specifically designed to enhance work ability.
我们之前比较了无定期访视的护士主导的随访项目（MyHealth）与常规随访对乳腺癌患者生活质量和心理健康的影响，结果显示MyHealth有积极作用。本研究旨在探讨MyHealth是否也能对自我报告的工作能力产生积极影响。
患者/材料与方法：共有288例可能活跃于劳动力市场的患者在接受早期乳腺癌初级治疗后（2017 - 2019年）被随机分为MyHealth组或对照随访组。MyHealth包括个体自我管理课程、电子症状监测以及医疗服务导航协助。对照随访包括每半年与医生进行一次门诊就诊。采用线性混合效应模型来评估MyHealth对随机分组后6个月、12个月、24个月和36个月时自我报告的工作能力的影响，工作能力通过工作能力得分（WAS）来衡量。
在最初的6个月里，两组的工作能力均显著提高（MyHealth组WAS平均增加：1.64，95%置信区间[CI]：1.26；2.02；对照组：1.57，95% CI：1.17；1.97），并且在36个月随访结束前持续略有增加但不显著（p值>0.13）。在基线时报告工作能力较差的患者中，改善尤为明显。MyHealth组和对照随访组患者的平均WAS差异不显著，在所有时间点均接近零（-0.21至0.48）。
与常规随访相比，MyHealth随访项目对自我报告的工作能力没有额外影响。未来的干预措施应针对工作能力较差的患者，并包括专门设计用于提高工作能力的组成部分。
