Carmel R
Arch Intern Med. 1985 Mar;145(3):484-5.
Pigmentation changes limited to skin appendages accompanied pernicious anemia in four patients. Two Latin-American patients, one with congenital and one with acquired pernicious anemia, had reddish hair while they were cobalamin deficient. With treatment, the new hair growth assumed its normal premorbid dark brown color. Two black patients with pernicious anemia had blue fingernails. The new nail growth after treatment was of normal color. Pigmentation changes seem to be more frequent in nonwhite than in white patients with cobalamin deficiency and may have various expressions.
四名恶性贫血患者出现了仅局限于皮肤附属器的色素沉着变化。两名拉丁裔患者，一名患有先天性恶性贫血，另一名患有后天性恶性贫血，在钴胺素缺乏时头发发红。经过治疗，新长出的头发恢复了病前正常的深棕色。两名患有恶性贫血的黑人患者指甲呈蓝色。治疗后新长出的指甲颜色正常。在钴胺素缺乏的患者中，色素沉着变化在非白人中似乎比白人更常见，并且可能有多种表现形式。
