Noppakun N, Swasdikul D
Arch Dermatol. 1986 Aug;122(8):896-9.
A case of reversible generalized hyperpigmentation of the skin and nails with reversible premature gray hair due to vitamin B12 deficiency is reported. The cause of the vitamin B12 deficiency in this patient was pernicious anemia. The pigmentation of his skin and hair returned to normal after treatment with intramuscular cyanocobalamin.
报告了一例因维生素B12缺乏导致皮肤和指甲可逆性全身色素沉着以及可逆性早发性白发的病例。该患者维生素B12缺乏的原因是恶性贫血。经肌肉注射氰钴胺治疗后,其皮肤和头发的色素沉着恢复正常。