Baran Burcu, Öksüm Solak Eda, Yetkin Nur Aleyna, Rabahoğlu Bilal, Tutar Nuri, Gülmez İnci, Oymak Fatma Sema
Department of Respiratory Diseases, Erciyes University Medical School, Kayseri, Turkey.
Dermatology and Venereology Department, Erciyes University Medical School, Kayseri, Turkey.
Arch Dermatol Res. 2025 Jan 7;317(1):185. doi: 10.1007/s00403-024-03734-2.
BACKGROUND/AIM: Psoriasis and Hidradenitis Suppurativa (HS) are chronic inflammatory skin conditions that significantly impact quality of life, sleep, and increase morbidity. This study aims to compare sleep quality and the risk of obstructive sleep apnea (OSA) in patients with these conditions. Additionally, it explores the relationships between sleep disorders, demographic factors, disease severity, and inflammatory markers.
The study included 25 HS and 50 psoriasis patients diagnosed and followed in the Dermatology Department of a tertiary healthcare institution. Disease severity was assessed using the HURLEY score for HS patients and the Psoriasis Area and Severity Index (PASI) for psoriasis patients. Sleep quality and OSA risk were evaluated using the Pittsburgh Sleep Quality Index (PSQI), Berlin, and STOP-Bang questionnaires.
A total of 75 patients participated, with 50 in the psoriasis group and 25 in the HS group. Of the participants, %41 were female, with a mean age of 36.4 ± 12.7 years. HS patients had significantly higher PSQI and STOP-Bang scores compared to psoriasis patients (p = 0.001 and p = 0.003, respectively). No significant associations were found between disease severity and questionnaire scores in either condition. However, the rate of high-risk OSA was higher in males (p = 0.004) and more prevalent in HS patients than in psoriasis patients (%64 vs. %26, p = 0.002).
HS patients face a significantly higher risk for OSA due to factors like obesity, smoking, increased neck and waist circumference, and elevated inflammation. Routine assessment of OSA risk using tools like the PSQI, Berlin, and STOP-Bang questionnaires is recommended for these patients.
背景/目的：银屑病和化脓性汗腺炎（HS）是慢性炎症性皮肤病，会严重影响生活质量、睡眠，并增加发病率。本研究旨在比较患有这些疾病的患者的睡眠质量和阻塞性睡眠呼吸暂停（OSA）风险。此外，还探讨了睡眠障碍、人口统计学因素、疾病严重程度和炎症标志物之间的关系。
该研究纳入了在一家三级医疗机构皮肤科诊断并随访的25例HS患者和50例银屑病患者。使用Hurley评分评估HS患者的疾病严重程度，使用银屑病面积和严重程度指数（PASI）评估银屑病患者的疾病严重程度。使用匹兹堡睡眠质量指数（PSQI）、柏林问卷和STOP-Bang问卷评估睡眠质量和OSA风险。
共有75名患者参与，其中银屑病组50名，HS组25名。参与者中，41%为女性，平均年龄为36.4±12.7岁。与银屑病患者相比，HS患者的PSQI和STOP-Bang评分显著更高（分别为p = 0.001和p = 0.003）。在这两种情况下，均未发现疾病严重程度与问卷评分之间存在显著关联。然而，男性的高风险OSA发生率更高（p = 0.004），且在HS患者中比在银屑病患者中更普遍（64%对26%，p = 0.002）。
由于肥胖、吸烟、颈围和腰围增加以及炎症升高，HS患者面临的OSA风险显著更高。建议对这些患者使用PSQI、柏林问卷和STOP-Bang问卷等工具进行OSA风险的常规评估。
