Farley Christopher, Phillips Stuart M, Smith-Turchyn Jenna, Brooks Dina
School of Rehabilitation Science, Faculty of Health Science, McMaster University, Hamilton, Ontario, Canada.
Department of Kinesiology, McMaster University, Hamilton, Ontario, Canada.
PLoS One. 2024 Dec 30;19(12):e0316451. doi: 10.1371/journal.pone.0316451. eCollection 2024.
Characteristics of chronic obstructive pulmonary disease (COPD) can include shortness of breath, chronic cough, sputum production and reduced exercise capacity. The sit-to-stand (STS) test variations (e.g., 5-repetition STS, 30-second STS) may be appropriate outcome measures to assess exercise capacity in people with COPD. To date, the measurement properties of the various STS tests in people with COPD have not been synthesized in a systematic review since the publication of the COnsensus-based Standards for the selection of health Measurement Instruments (COSMIN) guidelines. The purpose of this proposed systematic review is to synthesize the literature of the measurement properties of the STS test variations among people with COPD.
The review will be conducted with methods consistent with the COSMIN guidelines. Peer-reviewed publications will be included if they assessed the measurement properties (reliability, validity, responsiveness) of a STS test in community-dwelling adults with COPD. We will search six databases from inception. Study selection and data extraction will be conducted independently and in duplicate. We will assess the risk of bias using the COSMIN Risk of Bias tool, assess results against the COSMIN updated criteria for good measurement properties, and summarize certainty of evidence using the modified Grading of Recommendations Assessment, Development and Evaluation (GRADE) tool. Study results will be pooled by calculating weighted means and 95% confidence intervals or summarized narratively, as appropriate.
This will be the first systematic review to synthesize the measurement properties of the STS tests in people with COPD using the methods recommended by COSMIN. Consequently, its results will be robust and may help clinicians or researchers identify the best variation of the STS test to use in their practice.
慢性阻塞性肺疾病（COPD）的特征可能包括呼吸急促、慢性咳嗽、咳痰以及运动能力下降。坐立试验（STS）的不同形式（如5次重复坐立试验、30秒坐立试验）可能是评估COPD患者运动能力的合适结局指标。迄今为止，自基于共识的健康测量工具选择标准（COSMIN）指南发布以来，尚未对COPD患者中各种STS试验的测量特性进行系统评价。本拟议的系统评价旨在综合COPD患者中STS试验不同形式的测量特性的文献。
本评价将采用与COSMIN指南一致的方法进行。如果同行评审出版物评估了社区居住的COPD成年患者中STS试验的测量特性（信度、效度、反应度），则将其纳入。我们将从数据库建立之初开始检索六个数据库。研究选择和数据提取将独立进行并重复操作。我们将使用COSMIN偏倚风险工具评估偏倚风险，根据COSMIN更新的良好测量特性标准评估结果，并使用改良的推荐分级评估、制定和评价（GRADE）工具总结证据的确定性。研究结果将通过计算加权均值和95%置信区间进行合并，或酌情进行叙述性总结。
这将是首次使用COSMIN推荐的方法对COPD患者中STS试验的测量特性进行系统评价。因此，其结果将具有可靠性，并可能帮助临床医生或研究人员确定在其实践中使用的最佳STS试验形式。
