Cadoret R J, O'Gorman T W, Troughton E, Heywood E
Arch Gen Psychiatry. 1985 Feb;42(2):161-7. doi: 10.1001/archpsyc.1985.01790250055007.
In a sample of 127 male and 87 female adult adoptees, antisocial personality and alcohol abuse were related to biologic backgrounds and to environmental factors. In the men, alcohol abuse was increased by a background of problem drinking in first-degree biologic relatives and by drinking problems in the adoptive home. Antisocial personality occurred more frequently in men whose first-degree biologic relatives had antisocial behavior problems. In the women, alcohol abuse was increased in adoptees whose first-degree relatives had problem drinking. Increased alcohol abuse in men and women was not predicted by biologic first-degree relatives with antisocial problems, nor did increased frequency of antisocial personality occur in adoptees with biologic relatives with problem drinking. The results suggest specificity of inheritance of antisocial and alcoholic conditions and the importance of environmental factors.
在一个由127名成年男性和87名成年女性被收养者组成的样本中,反社会人格和酒精滥用与生物学背景及环境因素有关。在男性中,一级生物学亲属存在饮酒问题的背景以及收养家庭中的饮酒问题会增加酒精滥用的几率。反社会人格在一级生物学亲属有反社会行为问题的男性中更为常见。在女性中,一级亲属有饮酒问题的被收养者酒精滥用情况增多。有反社会问题的生物学一级亲属并不能预测男性和女性酒精滥用情况的增加,有饮酒问题的生物学亲属的被收养者中反社会人格出现的频率也没有增加。研究结果表明反社会和酗酒状况的遗传具有特异性以及环境因素的重要性。