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床边伤口牵开器袋状安置技术应用前后,腹裂患儿一期缝合与分期缝合的治疗效果。

The outcomes of treatment between primary closure and staged closure in gastroschisis in the pre and post era of the bedside wound retractor silo placement technique.

作者信息

Chantakhow Sireekarn, Thaivutinukul Pattamaporn, Tepmalai Kanokkan, Intatong Chutjongkol, Khorana Jiraporn

机构信息

Division of Pediatric Surgery, Department of Surgery, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.

Clinical Surgical Research Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.

出版信息

Pediatr Surg Int. 2025 Jan 7;41(1):59. doi: 10.1007/s00383-024-05940-5.

DOI:10.1007/s00383-024-05940-5
PMID:39775884
Abstract

PURPOSE

This study aimed to compare the treatment outcomes of the closure methods between pre and post-eras of bedside wound retractor silo placement technique (BSC).

METHODS

This retrospective cohort study included infants diagnosed with gastroschisis from 2006-2013, pre-BSC era, and from 2014-2021, BSC era. Infants who had fetal anomalies did not survive before receiving treatment and were treated with the delayed closure method were excluded. Pretreatment covariates were adjusted using propensity score in the multivariable logistic regression.

RESULTS

From 170 patients, 5 were excluded. 111 patients underwent primary closure (PC), 54 patients were staged closure (SC). Successful early enteral feeding was achieved in 70(42%) of patients. Among these patients, 52.2% were in the PC group, and 22.2% in the SC group. PC had a significantly higher rate of successful early enteral feeding compared to SC in the pre-BSC era (OR 21.98, 95%CI 2.59-186.51, p-value 0.005). The BSC era, there was no significant difference between the groups (OR 2.04, 95%CI 0.41-1.20, p-value 0.386). There were no differences in complications between PC and SC.

CONCLUSIONS

SC was not inferior in terms of achieving early feeding compared with PC. BSC is an acceptable procedure when a PC was not appropriate and accessible.

摘要

目的

本研究旨在比较床边伤口牵开器袋置入技术(BSC)前后两个时代不同闭合方法的治疗效果。

方法

这项回顾性队列研究纳入了2006年至2013年(BSC时代之前)以及2014年至2021年(BSC时代)被诊断为腹裂的婴儿。有胎儿异常且在接受治疗前未存活以及采用延迟闭合方法治疗的婴儿被排除。在多变量逻辑回归中使用倾向评分对预处理协变量进行调整。

结果

170例患者中,5例被排除。111例患者接受了一期闭合(PC),54例患者接受了分期闭合(SC)。70例(42%)患者成功实现了早期肠内喂养。在这些患者中,PC组占52.2%,SC组占22.2%。在BSC时代之前,PC组早期肠内喂养成功的比例显著高于SC组(比值比21.98,95%置信区间2.59 - 186.51,p值0.005)。在BSC时代,两组之间无显著差异(比值比2.04,95%置信区间0.41 - 1.20,p值0.386)。PC和SC在并发症方面无差异。

结论

在实现早期喂养方面,SC并不比PC差。当PC不合适或无法实施时,BSC是一种可接受的手术方法。

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The outcomes of treatment between primary closure and staged closure in gastroschisis in the pre and post era of the bedside wound retractor silo placement technique.床边伤口牵开器袋状安置技术应用前后,腹裂患儿一期缝合与分期缝合的治疗效果。
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本文引用的文献

1
Management of Gastroschisis: Timing of Delivery, Antibiotic Usage, and Closure Considerations (A Systematic Review From the American Pediatric Surgical Association Outcomes & Evidence Based Practice Committee).腹裂的管理:分娩时机、抗生素使用及闭合考虑因素(美国小儿外科协会结果与循证实践委员会的系统评价)
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Gastroschisis: Impact of Bedside Closure on Ventilator-Associated Outcomes.先天性腹裂:床边关闭术对呼吸机相关结局的影响。
Eur J Pediatr Surg. 2022 Feb;32(1):105-110. doi: 10.1055/s-0041-1741541. Epub 2022 Jan 10.
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Gastroschisis with intestinal atresia leads to longer hospitalization and poor feeding outcomes.
腹裂合并肠闭锁会导致住院时间延长及喂养效果不佳。
J Perinatol. 2022 Feb;42(2):254-259. doi: 10.1038/s41372-021-01131-5. Epub 2021 Jun 21.
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Gastroschisis: a systematic review of diagnosis, prognosis and treatment.先天性腹裂:诊断、预后和治疗的系统评价。
J Matern Fetal Neonatal Med. 2022 Dec;35(25):6199-6212. doi: 10.1080/14767058.2021.1909563. Epub 2021 Apr 25.
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Sutureless vs sutured abdominal wall closure for gastroschisis: Operative characteristics and early outcomes from the Midwest Pediatric Surgery Consortium.无缝线与缝线关腹治疗腹裂的比较:中西部小儿外科学会的手术特点和早期结果。
J Pediatr Surg. 2020 Nov;55(11):2284-2288. doi: 10.1016/j.jpedsurg.2020.02.017. Epub 2020 Feb 20.
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Immediate versus silo closure for gastroschisis: Results of a large multicenter study.立即关闭与间隔关闭治疗先天性腹裂的对比:一项大型多中心研究结果。
J Pediatr Surg. 2020 Jul;55(7):1280-1285. doi: 10.1016/j.jpedsurg.2019.08.002. Epub 2019 Aug 22.
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Closure methods in gastroschisis.腹裂的闭合方法。
Semin Pediatr Surg. 2018 Oct;27(5):304-308. doi: 10.1053/j.sempedsurg.2018.08.009. Epub 2018 Aug 28.
8
Single center protocol driven care in 150 patients with gastroschisis 1998-2017: collaboration improves results.1998 - 2017年150例腹裂患儿的单中心协议驱动式护理:合作改善治疗结果
Pediatr Surg Int. 2018 Nov;34(11):1171-1176. doi: 10.1007/s00383-018-4349-7. Epub 2018 Sep 25.
9
The factors associated with successful early enteral feeding in gastroschisis.与腹裂患儿早期肠内营养成功相关的因素。
Pediatr Surg Int. 2018 Jul;34(7):743-748. doi: 10.1007/s00383-018-4282-9. Epub 2018 May 25.
10
Primary Closure versus Bedside Silo and Delayed Closure for Gastroschisis: A Truncated Prospective Randomized Trial.先天性腹裂的一期缝合与床边袋状缝合法及延迟缝合:一项截尾前瞻性随机试验
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