Chantakhow Sireekarn, Thaivutinukul Pattamaporn, Tepmalai Kanokkan, Intatong Chutjongkol, Khorana Jiraporn
Division of Pediatric Surgery, Department of Surgery, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Clinical Surgical Research Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Pediatr Surg Int. 2025 Jan 7;41(1):59. doi: 10.1007/s00383-024-05940-5.
This study aimed to compare the treatment outcomes of the closure methods between pre and post-eras of bedside wound retractor silo placement technique (BSC).
This retrospective cohort study included infants diagnosed with gastroschisis from 2006-2013, pre-BSC era, and from 2014-2021, BSC era. Infants who had fetal anomalies did not survive before receiving treatment and were treated with the delayed closure method were excluded. Pretreatment covariates were adjusted using propensity score in the multivariable logistic regression.
From 170 patients, 5 were excluded. 111 patients underwent primary closure (PC), 54 patients were staged closure (SC). Successful early enteral feeding was achieved in 70(42%) of patients. Among these patients, 52.2% were in the PC group, and 22.2% in the SC group. PC had a significantly higher rate of successful early enteral feeding compared to SC in the pre-BSC era (OR 21.98, 95%CI 2.59-186.51, p-value 0.005). The BSC era, there was no significant difference between the groups (OR 2.04, 95%CI 0.41-1.20, p-value 0.386). There were no differences in complications between PC and SC.
SC was not inferior in terms of achieving early feeding compared with PC. BSC is an acceptable procedure when a PC was not appropriate and accessible.
本研究旨在比较床边伤口牵开器袋置入技术(BSC)前后两个时代不同闭合方法的治疗效果。
这项回顾性队列研究纳入了2006年至2013年(BSC时代之前)以及2014年至2021年(BSC时代)被诊断为腹裂的婴儿。有胎儿异常且在接受治疗前未存活以及采用延迟闭合方法治疗的婴儿被排除。在多变量逻辑回归中使用倾向评分对预处理协变量进行调整。
170例患者中,5例被排除。111例患者接受了一期闭合(PC),54例患者接受了分期闭合(SC)。70例(42%)患者成功实现了早期肠内喂养。在这些患者中,PC组占52.2%,SC组占22.2%。在BSC时代之前,PC组早期肠内喂养成功的比例显著高于SC组(比值比21.98,95%置信区间2.59 - 186.51,p值0.005)。在BSC时代,两组之间无显著差异(比值比2.04,95%置信区间0.41 - 1.20,p值0.386)。PC和SC在并发症方面无差异。
在实现早期喂养方面,SC并不比PC差。当PC不合适或无法实施时,BSC是一种可接受的手术方法。