Mayr Lena Maria, Besse-Flütsch Nicole, Smigielski Lukasz, Walitza Susanne, Pauli Dagmar
Department of Child and Adolescent Psychiatry, University of Zurich, Zurich, Switzerland.
Neuroscience Center Zurich, Swiss Federal Institute of Technology and University of Zurich, Zurich, Switzerland.
Eur Eat Disord Rev. 2025 May;33(3):608-615. doi: 10.1002/erv.3170. Epub 2025 Jan 7.
Family-based treatment (FBT) is promising for treating adolescents with anorexia nervosa, but long-term remission rates are modest. Home treatment (HT) as a supplement to FBT aims to enhance sustainability and effectiveness by supporting recovery within the family. This study compares the cost-effectiveness of FBT alone versus FBT with additional HT for adolescents with anorexia nervosa.
This cost-effectiveness analysis is based on a non-randomized pilot study, which examined the effectiveness of HT for adolescents with anorexia nervosa, disregarding the financial aspects. HT involved therapeutic interventions delivered in the patient's home environment, while FBT involved structured therapy sessions at the psychiatric clinic. Data from 61 patients were analysed, with 40 receiving FBT + HT and 21 receiving FBT only. Costs included FBT sessions, HT sessions, and inpatient treatment. Effectiveness was measured by weight restoration at thresholds of expected body weight (EBW) > 85% and EBW > 95%.
FBT + HT promoted greater weight restoration within three months compared to FBT alone (70% vs. 52% at EBW > 85%; 38% vs. 29% at EBW > 95%). FBT + HT was more cost-effective, with lower average costs per patient meeting weight restoration criteria (8243 vs. 20,446 Swiss francs at EBW > 85%; 15,387 vs. 37,485 Swiss francs at EBW > 95%). Inpatient treatment accounted for most of the cost, with FBT + HT reducing hospitalisation needs.
FBT with additional HT is a more cost-effective treatment for adolescents with anorexia nervosa. Although the cost-effectiveness index was relatively high, effective treatment could reduce the long-term burdens of this disorder. Larger long-term studies are needed to validate these findings and assess sustained cost-effectiveness.
基于家庭的治疗(FBT)在治疗神经性厌食症青少年方面颇具前景,但长期缓解率一般。家庭治疗(HT)作为FBT的补充,旨在通过支持家庭内部的康复来提高可持续性和有效性。本研究比较了单纯FBT与FBT联合额外HT治疗神经性厌食症青少年的成本效益。
本成本效益分析基于一项非随机试点研究,该研究考察了HT对神经性厌食症青少年的有效性,未考虑财务方面。HT包括在患者家庭环境中进行的治疗干预,而FBT包括在精神科诊所进行的结构化治疗课程。分析了61名患者的数据,其中40名接受FBT + HT,21名仅接受FBT。成本包括FBT疗程、HT疗程和住院治疗。有效性通过预期体重(EBW)>85%和EBW>95%时的体重恢复来衡量。
与单纯FBT相比,FBT + HT在三个月内促进了更大程度的体重恢复(EBW>85%时为70%对52%;EBW>95%时为38%对29%)。FBT + HT更具成本效益,达到体重恢复标准的每位患者平均成本更低(EBW>85%时为8243瑞士法郎对20446瑞士法郎;EBW>95%时为15387瑞士法郎对37485瑞士法郎)。住院治疗占成本的大部分,FBT + HT减少了住院需求。
FBT联合额外HT对神经性厌食症青少年是一种更具成本效益的治疗方法。尽管成本效益指数相对较高,但有效的治疗可以减轻这种疾病的长期负担。需要更大规模的长期研究来验证这些发现并评估持续的成本效益。