Savinova L I
Arkh Anat Gistol Embriol. 1985 Jan;88(1):71-5.
In 56 rabbits kept in tight cages for 4, 8, 12, 16 and 20 weeks, effect of hypokinesia on structure of hemomicrocirculatory bed of the retina has been studied. The retina is digested in tripsin and then it is exfoliated, and the vessels are stained after Shiff. Diameters of arterioles, capillaries and venules are measured, their relations to each other and number of vessels per square unit are taken into consideration. Restriction of the motor activity for 4 weeks results in narrowing of arterioles, capillaries and venules, in increasing venuloarteriolar coefficient, in decreasing number of vessels per square unit, as compared to the norm. In 8 weeks of hypokinesia the diameter of all links of the hemomicrocirculatory bed is evenly increasing, but it does not reach the normal value; the number of the vessels is keeping to decrease; the venuloarteriolar coefficient is at the same level. In 12, 16 and 20 weeks changes in the diameter and the number of the vessels are poorly pronounced, have a wavy character and diversily directed. The value of the venuloarteriolar coefficient is kept constant. As a whole, the data obtained demonstrate that at a long hypokinesia the animals adapt to the new conditions of existence, and the state of the reticular hemomicrocirculatory bed stabilizes.
在56只被关在狭窄笼子里4周、8周、12周、16周和20周的兔子身上，研究了运动不足对视网膜血液微循环床结构的影响。将视网膜用胰蛋白酶消化，然后进行剥离，血管用席夫试剂染色后，测量小动脉、毛细血管和小静脉的直径，考虑它们之间的关系以及每平方单位的血管数量。与正常情况相比，运动活动受限4周会导致小动脉、毛细血管和小静脉变窄，小静脉与小动脉的系数增加，每平方单位的血管数量减少。运动不足8周时，血液微循环床所有环节的直径均匀增加，但未达到正常值；血管数量持续减少；小静脉与小动脉的系数保持在同一水平。在12周、16周和20周时，血管直径和数量的变化不明显，呈波浪状且方向多样。小静脉与小动脉的系数值保持不变。总体而言，所获得的数据表明，长期运动不足时动物会适应新的生存条件，视网膜血液微循环床的状态会稳定下来。
