Zotova N I
Arkh Anat Gistol Embriol. 1977 Oct;73(10):49-55.
Experiments were carried out in 37 animals (33 test animals and 4 controls). Hypokinesia was produced by keeping the animals in small cages. After 1, 2, 3, 4, 5, 6, 8, 12, 16 weeks of restricted mobility the animals were killed. The brain blood vessels were injected with dye-stuffs and examined in cleared sections. In 9 animals (2 controls and 7 test animals) the brain blood vessels were studied histochemically. Hypokinesia was stated to change significantly the angio-architectonics of the telencephalon. During first three weeks of restricted mobility, the blood vessels change but a little. By that time, together with unchanged arteries and veins, narrow arteries and a great number of dilated veins are encountered. The density of the blood vessel network is altered. Later on, after 4 weeks, more profound changes in the blood vessels occur: they become tortuous, deformed with disturbance of their usual orientation of course. These changes are specific for all the parts of the telencephalon. They increase with the time of hypokinesia.
对37只动物（33只试验动物和4只对照动物）进行了实验。通过将动物饲养在小笼子里制造运动功能减退。在限制活动1、2、3、4、5、6、8、12、16周后，处死动物。向脑内血管注射染料并在透明切片中进行检查。对9只动物（2只对照动物和7只试验动物）的脑内血管进行了组织化学研究。结果表明，运动功能减退显著改变了端脑的血管构筑。在限制活动的前三周，血管变化不大。此时，除了动脉和静脉没有变化外，还发现了狭窄的动脉和大量扩张的静脉。血管网络的密度发生了改变。4周后，血管出现更明显的变化：血管变得迂曲、变形，其正常走行方向受到干扰。这些变化在端脑的所有部位都是特异性的。它们随着运动功能减退的时间而增加。
