Ma Jian, Ren Feiqiang, Lu Shikuan, Ye Yan, Xu Lei, Zhang Peihai, Ma Ziyang
Department of Urology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Department of Urology, Chongqing Hospital of Traditional Chinese Medicine, Chongqing, China.
Arab J Urol. 2024 Sep 11;23(1):75-83. doi: 10.1080/20905998.2024.2400628. eCollection 2025.
Overactive bladder (OAB) is a common lower urinary tract symptom of bladder storage dysfunction. Numerous studies have evaluated the efficacy and safety of acupuncture therapy for overactive bladder, but clinical programs and data were largely inconsistent. Therefore, it is necessary to summarize and analyze the published clinical research data in the field. We aimed to perform an umbrella review of systematic reviews and meta-analyses (SRs/MAs) to evaluate the efficacy and safety of acupuncture therapy.
We searched PubMed, the Cochrane Library, Embase, and three China databases (CNKI, VIP, and Wanfang Data) from the establishment of each database to 1 February 2024. Evaluation tools used the AMSTAR 2 tool and the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) rating system.
A total of seven SRs/MAs were included. Six reviews were rated as critically low on overall confidence and one review was low on confidence based on the AMSTAR 2 tool. The GRADE evidence quality rating demonstrated that the quality of evidence for one outcome indicator was moderate, five were low, and 28 were critically low. Twenty-three of the 34 outcome indicators exhibited a significant improvement compared to the control group. The present research results supported acupuncture as a complementary therapy for OAB patients, but the evidence should be considered carefully due to the methodological flaws identified.
Our study demonstrated that acupuncture, as traditional Chinese medicine, regulates bladder qi and has a good therapeutic effect in the treatment of OAB.
膀胱过度活动症（OAB）是膀胱储尿功能障碍常见的下尿路症状。众多研究评估了针刺疗法治疗膀胱过度活动症的疗效和安全性，但临床方案和数据在很大程度上并不一致。因此，有必要总结和分析该领域已发表的临床研究数据。我们旨在对系统评价和荟萃分析（SRs/MAs）进行伞形综述，以评估针刺疗法的疗效和安全性。
我们检索了PubMed、Cochrane图书馆、Embase以及三个中国数据库（中国知网、维普资讯和万方数据），检索时间从各数据库建立至2024年2月1日。评估工具采用AMSTAR 2工具和推荐分级评估、制定与评价（GRADE）评级系统。
共纳入7篇SRs/MAs。根据AMSTAR 2工具，6篇综述的总体信心评级为极低，1篇综述的信心评级为低。GRADE证据质量评级显示，1个结局指标的证据质量为中等，5个为低，28个为极低。34个结局指标中有23个与对照组相比有显著改善。本研究结果支持针刺作为OAB患者的辅助治疗方法，但鉴于已发现的方法学缺陷，对证据应谨慎考虑。
我们的研究表明，针刺作为中医治疗方法，可调节膀胱气机，对OAB的治疗有良好疗效。
