Huang Min-Ping, Hsueh Shu-Kai, Chung Wen-Jung, Wu Chiung-Jen
Department of Internal Medicine, Division of Cardiology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Acta Cardiol Sin. 2025 Jan;41(1):94-105. doi: 10.6515/ACS.202501_41(1).20241024A.
This study aims to verify the feasibility and safety of percutaneous coronary intervention (PCI) after a distal transradial approach (dTRA) with radial artery occlusion (RAO) recanalization.
Between July 2018 and January 2022, 30 patients underwent PCI following attempted RAO recanalization via dTRA. Among these cases, the target radial arteries could not be recanalized in five patients, necessitating alternative vascular access. The remaining 25 patients with successful RAO recanalization were divided into a standard group (n = 19) and tough group (n = 6), the latter requiring more than 10 minutes and complex techniques and devices for recanalization.
The procedural success rate was 96.7%, with vascular access-site complications occurring in 20% of the cases, including five perforations easily managed with prolonged balloon inflation and one pseudoaneurysm without flow limitation. In the tough group, no significant increase in procedural complications, access-site vascular complications, or total major adverse cardiac and cerebrovascular events was observed. However, Doppler ultrasound one month later for the recanalized radial artery revealed a significantly higher rate of severe stenosis and re-occlusion at 100% compared to 10% in the standard group, as supported by receiver operating characteristic curve analysis.
The feasibility and safety of PCI following RAO recanalization via dTRA were acceptable. We propose a 10-minute threshold to differentiate between standard and tough groups during RAO recanalization. Given the uncertainty of long-term patency in recanalized RAs, the primary goal in tough cases is to ensure the guide catheter reaches the ascending aorta for subsequent PCI.
本研究旨在验证经远端桡动脉入路(dTRA)并进行桡动脉闭塞(RAO)再通后行经皮冠状动脉介入治疗(PCI)的可行性和安全性。
2018年7月至2022年1月期间,30例患者经dTRA尝试进行RAO再通后接受了PCI治疗。在这些病例中,有5例患者的目标桡动脉未能成功再通,需要采用其他血管通路。其余25例RAO再通成功的患者被分为标准组(n = 19)和困难组(n = 6),后者再通需要超过10分钟以及复杂的技术和器械。
手术成功率为96.7%,20%的病例出现血管入路部位并发症,包括5例通过延长球囊扩张轻松处理的穿孔和1例无血流受限的假性动脉瘤。在困难组中,未观察到手术并发症、入路部位血管并发症或总的主要不良心脑血管事件显著增加。然而,再通桡动脉一个月后的多普勒超声显示,与标准组10%的严重狭窄和再闭塞率相比,困难组该比率显著更高,为100%,这得到了受试者工作特征曲线分析的支持。
经dTRA进行RAO再通后行PCI的可行性和安全性是可以接受的。我们建议在RAO再通期间以10分钟为界区分标准组和困难组。鉴于再通桡动脉长期通畅性的不确定性,困难病例的主要目标是确保引导导管到达升主动脉以便后续进行PCI。