Scott A B, Kennedy R A, Stubbs H A
Arch Ophthalmol. 1985 Mar;103(3):347-50. doi: 10.1001/archopht.1985.01050030043017.
Thirty-nine patients with blepharospasm were treated with injections of botulinum A toxin into the lid and brow. The maximum number of injections in one patient was 16 over a period of 24 months. A reduction of abnormal movement occurred in all patients, lasting up to 170 days. Both the amount and the duration of effect were dose dependent. Reinjection for recurrence had effects similar to the original injection. Tearing, dry-eye symptoms, or transient ptosis occurred in 20% of injections, especially in patients who had had previous eyelid surgery.
39例睑痉挛患者接受了肉毒杆菌A毒素注射到眼睑和眉部的治疗。在24个月的时间里，一名患者的最大注射次数为16次。所有患者的异常运动均有减少，持续时间长达170天。效果的量和持续时间均呈剂量依赖性。复发时再次注射的效果与初次注射相似。20%的注射出现流泪、干眼症状或短暂上睑下垂，尤其是既往有眼睑手术史的患者。
