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神经肌肉疾病中的晚期心力衰竭治疗

Advanced Heart Failure Therapies in Neuromuscular Diseases.

作者信息

Agdamag Arianne Clare, Nandar Phoo Pwint, Tang W H Wilson

机构信息

Section of Advanced Heart Failure and Transplantation Medicine, Department of Cardiovascular Medicine, Miller Family Heart, Vascular and Thoracic Institute, Robert and Suzanne Tomsich, Cleveland Clinic, Cleveland, OH 44195, USA.

Section of Advanced Heart Failure, Department of Medicine, MetroHealth Medical Center, Cleveland, OH 44109, USA.

出版信息

Curr Treat Options Cardiovasc Med. 2024 Aug;26(8):255-270. doi: 10.1007/s11936-024-01046-2. Epub 2024 Jun 25.

Abstract

PURPOSE OF REVIEW

The main objective of this review article is to discuss the prevalence, utilization, and outcomes associated with advanced heart failure therapies among patients with neuromuscular disorders.

RECENT FINDINGS

Neuromuscular disorders often have multisystem involvement with a high prevalence of cardiovascular pathology. With the improvement in management of respiratory related complications, heart failure is now the leading cause of mortality in this patient population. Advanced heart failure therapies with durable left ventricular assist devices and heart transplantation have proven to be feasible and safe treatment options in selected patients.

SUMMARY

Management of neuromuscular disease involves multidisciplinary team involvement given the systemic nature of the disease. Early recognition and close monitoring of these patients will allow for timely initiation of advanced heart failure therapies that can lead to successful outcomes.

摘要

综述目的

本文综述的主要目的是讨论神经肌肉疾病患者中晚期心力衰竭治疗的患病率、应用情况及治疗结果。

最新发现

神经肌肉疾病常累及多系统,心血管病变的患病率很高。随着呼吸相关并发症管理的改善,心力衰竭现已成为该患者群体的主要死亡原因。对于部分选定患者,使用耐用的左心室辅助装置和心脏移植的晚期心力衰竭治疗已被证明是可行且安全的治疗选择。

总结

鉴于神经肌肉疾病的全身性,其管理需要多学科团队的参与。对这些患者的早期识别和密切监测将有助于及时启动晚期心力衰竭治疗,从而取得成功的治疗结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1495/11706575/834c06b2aae6/nihms-2006362-f0001.jpg

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