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解读人乳头瘤病毒在妇科肿瘤学中的影响:一项叙述性综述

Decoding impact of human papillomavirus in gynecological oncology: a narrative review.

作者信息

Sarker Md Safiullah, Pervez Mohammed Moshtaq

机构信息

Virology Laboratory, Programme for Emerging Infections, Infectious Diseases Division, icddr,b, Dhaka, Bangladesh.

Hospital, Nutrition and Clinical Services Division, icddr,b, Dhaka, Bangladesh.

出版信息

Obstet Gynecol Sci. 2025 Jan;68(1):30-42. doi: 10.5468/ogs.24226. Epub 2025 Jan 9.

Abstract

Human papillomavirus (HPV) is a key factor in gynecological oncology. This narrative review investigates the complex connection between HPV and various gynecological cancers. For a comprehensive exploration, we examined the association between persistent HPV infection and cervical cancer and its global prevalence. Beyond the cervix, we navigated the linkages between HPV and other gynecological malignancies, shedding light on vulvar, vaginal, anal, and oropharyngeal cancers. The narrative extends to discuss the critical role of HPV vaccination in preventing these cancers and exploring challenges, controversies, and future perspectives in the field. As we have described the impact of HPV, this review underscores the significance of ongoing research and public health endeavors in shaping the trajectory of gynecological oncology.

摘要

人乳头瘤病毒(HPV)是妇科肿瘤学中的一个关键因素。这篇叙述性综述探讨了HPV与各种妇科癌症之间的复杂联系。为了进行全面探究,我们研究了持续性HPV感染与宫颈癌之间的关联及其全球流行率。除了子宫颈,我们还梳理了HPV与其他妇科恶性肿瘤之间的联系,阐明了外阴癌、阴道癌、肛门癌和口咽癌的情况。该叙述还延伸至讨论HPV疫苗接种在预防这些癌症方面的关键作用,并探讨该领域的挑战、争议和未来展望。正如我们所描述的HPV的影响,这篇综述强调了持续研究和公共卫生努力在塑造妇科肿瘤学发展轨迹方面的重要性。

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Positive results bias in randomized controlled trials in gynecologic oncology.妇科肿瘤学随机对照试验中的阳性结果偏倚
Arch Gynecol Obstet. 2024 Apr;309(4):1681-1683. doi: 10.1007/s00404-023-07099-1. Epub 2023 Jun 13.

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