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微创二尖瓣修复的快速康复方案

Rapid-recovery protocol for minimally invasive mitral valve repair.

作者信息

Brown Amy, Hassanabad Ali Fatehi, Moen Jolene, Wiens Karen, Gregory Alexander J, Parhar Ken Kuljit S, Adams Corey, Kent William D T

机构信息

Department of Cardiac Sciences, Libin Cardiovascular Institute, University of Calgary, Calgary, Alberta, Canada.

Department of Anesthesiology, Libin Cardiovascular Institute, University of Calgary, Calgary, Alberta, Canada.

出版信息

JTCVS Open. 2024 Aug 23;22:49-60. doi: 10.1016/j.xjon.2024.08.006. eCollection 2024 Dec.

Abstract

BACKGROUND

Minimally invasive mitral valve repair (MIMVR), often performed within specialized care pathways, has been shown to reduce hospital length of stay and improve patient recovery. The relative value of rapid-recovery protocols as a component of care pathways, including enhanced recovery programs (ERPs), has not been well described. This study compared clinical outcomes following implementation of a new, comprehensive rapid-recovery protocol within a previously established, mature ERP for patients undergoing MIMVR.

METHODS

The rapid-recovery protocol was developed and implemented by a multidisciplinary team to further optimize patient recovery within an existing ERP. The protocol was applied to 75 consecutive patients undergoing MIMVR between September 2022 and December 2023. Outcomes were compared retrospectively to 75 ERP control patients who did not receive the rapid-recovery protocol but experienced the ERP. The primary outcome was a composite of discharge from the intensive care unit (ICU) by postoperative day (POD) 1, discharge to home by POD 4, and no all-cause hospital readmission by 30 days.

RESULTS

Baseline characteristics were similar in the 2 groups. Patients in the rapid-recovery group achieved the primary composite outcome significantly more often compared to the control group (60% vs 40%, respectively). There was no between-group difference in postoperative complications. Multivariable logistic regression showed that age ≤60 years was significantly associated with rapid-recovery protocol success. Clinical barriers to achieving individual components of the primary outcome were described.

CONCLUSIONS

A rapid-recovery protocol for MIMVR was associated with early ICU and hospital discharge. These benefits were safely achieved without any increase in hospital readmission, morbidity, or mortality up to 30 days postoperatively.

摘要

背景

微创二尖瓣修复术(MIMVR)通常在专门的护理路径中进行,已被证明可缩短住院时间并改善患者恢复情况。快速康复方案作为护理路径的一个组成部分,包括强化康复计划(ERP),其相对价值尚未得到充分描述。本研究比较了在先前建立的、成熟的ERP中为接受MIMVR的患者实施新的、全面的快速康复方案后的临床结果。

方法

快速康复方案由一个多学科团队制定并实施,以在现有的ERP中进一步优化患者恢复。该方案应用于2022年9月至2023年12月期间连续接受MIMVR的75例患者。将结果与75例未接受快速康复方案但接受了ERP的对照组患者进行回顾性比较。主要结局是术后第1天从重症监护病房(ICU)出院、术后第4天出院回家以及30天内无全因再入院的综合情况。

结果

两组的基线特征相似。与对照组相比,快速康复组患者更频繁地实现了主要综合结局(分别为60%和40%)。术后并发症在组间无差异。多变量逻辑回归显示,年龄≤60岁与快速康复方案的成功显著相关。描述了实现主要结局各个组成部分的临床障碍。

结论

MIMVR的快速康复方案与早期ICU出院和出院相关。在术后30天内,这些益处得以安全实现,且未增加再入院率、发病率或死亡率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed1d/11704579/a0da0304d0f8/fx1.jpg

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