Lei Fei, Hu Xiaotao
Department of Stomatology, Second Affiliated Hospital of Xi'an Medical University, Xi'an, Shaanxi 710000, P.R. China.
Department of Stomatology, Shaanxi Province Second People's Hospital (Shaanxi Province Geriatric Hospital), Xi'an, Shaanxi 710000, P.R. China.
Biomed Rep. 2024 Dec 20;22(3):37. doi: 10.3892/br.2024.1915. eCollection 2025 Mar.
Oral health and sleep quality are critical components of overall health, but their relationship remains poorly understood. The present meta-analysis therefore investigates the association between oral health and sleep quality, synthesizing evidence from diverse populations. To this aim, a comprehensive search strategy identified 311 articles, from which 8 studies encompassing 18 comparisons met the inclusion criteria. These studies, conducted between 2015 and 2023, included 36,559 participants across various countries. Oral health was assessed using indices such as the Decayed, Missing, and Filled Teeth Index and gingival indices. At the same time, sleep quality was measured using tools such as the Pittsburgh Sleep Quality Index and Epworth Sleepiness Scale. The results of the meta-analysis revealed a significant association between poorer oral health and poorer sleep quality, with a standardized mean difference of 2.166 [95% confidence interval (95% CI), 0.677-3.655; P=0.004]. Sensitivity analyses confirmed the robustness of the findings, and publication bias assessments indicated no significant bias. Precision interval analysis showed a mean effect size of 2.17 with a 95% CI of -4.83 to 9.16, suggesting variability in the strength of the association across populations. In conclusion, the results of the present meta-analysis provide strong evidence for a significant link between oral health and sleep quality, highlighting the importance of considering oral health in the management of sleep disorders. Future research should focus on longitudinal studies and standardized measurement tools to further elucidate this relationship and inform public health strategies aimed at improving both oral health and sleep quality.
口腔健康和睡眠质量是整体健康的关键组成部分，但它们之间的关系仍未得到充分理解。因此，本荟萃分析旨在研究口腔健康与睡眠质量之间的关联，综合来自不同人群的证据。为此，采用全面的检索策略共识别出311篇文章，其中8项研究包含18组比较符合纳入标准。这些研究在2015年至2023年期间进行，涵盖了不同国家的36,559名参与者。使用诸如龋失补牙指数和牙龈指数等指标评估口腔健康。同时，使用匹兹堡睡眠质量指数和爱泼华嗜睡量表等工具测量睡眠质量。荟萃分析结果显示，口腔健康较差与睡眠质量较差之间存在显著关联，标准化平均差为2.166[95%置信区间(95%CI)，0.677 - 3.655；P = 0.004]。敏感性分析证实了研究结果的稳健性，发表偏倚评估表明无显著偏倚。精确区间分析显示平均效应大小为2.17，95%CI为 - 4.83至9.16，表明不同人群之间关联强度存在差异。总之，本荟萃分析结果为口腔健康与睡眠质量之间的显著联系提供了有力证据，突出了在睡眠障碍管理中考虑口腔健康的重要性。未来的研究应侧重于纵向研究和标准化测量工具，以进一步阐明这种关系，并为旨在改善口腔健康和睡眠质量的公共卫生策略提供依据。
