• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

应用伸膝装置转移治疗股骨远端恶性间叶性肿瘤:1例报告及手术技术

Treatment of Distal Femoral Malignant Mesenchymal Tumor With Extensor Mechanism Transfer: A Case Report and Surgical Technique.

作者信息

Celayir Arın, Ozturk Burak, Kavak Şeyhmus, Ozsahin Mahmut K, Botanlioglu Huseyin

机构信息

Orthopaedics and Traumatology, Cerrahpaşa Faculty of Medicine, Istanbul University-Cerrahpaşa, Istanbul, TUR.

出版信息

Cureus. 2024 Dec 7;16(12):e75303. doi: 10.7759/cureus.75303. eCollection 2024 Dec.

DOI:10.7759/cureus.75303
PMID:39781131
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11707006/
Abstract

Malignant mesenchymal tumors are a diverse group of aggressive cancers originating from mesenchymal cells in connective tissues such as bone, muscle, cartilage, and fat. These tumors often invade surrounding tissues and metastasize to distant organs, posing significant treatment challenges. Among them, malignant mesenchymal tumors located in the distal femur are particularly rare, with limited reports detailing effective surgical and functional reconstruction strategies following wide resection. This case report focuses on the treatment of a distal femoral malignant mesenchymal tumor managed at our clinic, where wide resection was followed by reconstruction using a tumor resection prosthesis and extensor mechanism transfer. The report highlights the innovative surgical technique employed to restore extensor function while maintaining structural integrity, addressing a critical gap in the literature. By sharing insights into this approach, this report aims to contribute to the growing body of knowledge on limb salvage surgery and improve outcomes for patients with similar complex conditions.

摘要

恶性间充质肿瘤是一组源自骨、肌肉、软骨和脂肪等结缔组织中间充质细胞的侵袭性癌症。这些肿瘤常侵犯周围组织并转移至远处器官,带来重大的治疗挑战。其中,位于股骨远端的恶性间充质肿瘤尤为罕见,关于广泛切除术后有效的手术及功能重建策略的详细报道有限。本病例报告聚焦于我院诊治的一例股骨远端恶性间充质肿瘤,采用肿瘤切除假体及伸肌机制转移进行广泛切除术后重建。该报告突出了所采用的创新手术技术,即在维持结构完整性的同时恢复伸肌功能,填补了文献中的关键空白。通过分享对该方法的见解,本报告旨在为肢体挽救手术不断增长的知识体系做出贡献,并改善患有类似复杂病症患者的治疗效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8bc/11707006/e6526699ce48/cureus-0016-00000075303-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8bc/11707006/624e3ec50072/cureus-0016-00000075303-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8bc/11707006/d88a1e1ad7b4/cureus-0016-00000075303-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8bc/11707006/d71547dde6e8/cureus-0016-00000075303-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8bc/11707006/719ab93eca3d/cureus-0016-00000075303-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8bc/11707006/9733aef3475b/cureus-0016-00000075303-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8bc/11707006/f1638f9dde34/cureus-0016-00000075303-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8bc/11707006/7d50ae446da9/cureus-0016-00000075303-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8bc/11707006/e6526699ce48/cureus-0016-00000075303-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8bc/11707006/624e3ec50072/cureus-0016-00000075303-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8bc/11707006/d88a1e1ad7b4/cureus-0016-00000075303-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8bc/11707006/d71547dde6e8/cureus-0016-00000075303-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8bc/11707006/719ab93eca3d/cureus-0016-00000075303-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8bc/11707006/9733aef3475b/cureus-0016-00000075303-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8bc/11707006/f1638f9dde34/cureus-0016-00000075303-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8bc/11707006/7d50ae446da9/cureus-0016-00000075303-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8bc/11707006/e6526699ce48/cureus-0016-00000075303-i08.jpg

相似文献

1
Treatment of Distal Femoral Malignant Mesenchymal Tumor With Extensor Mechanism Transfer: A Case Report and Surgical Technique.应用伸膝装置转移治疗股骨远端恶性间叶性肿瘤:1例报告及手术技术
Cureus. 2024 Dec 7;16(12):e75303. doi: 10.7759/cureus.75303. eCollection 2024 Dec.
2
Cementless, Cruciate-Retaining Primary Total Knee Arthroplasty Using Conventional Instrumentation: Technical Pearls and Intraoperative Considerations.使用传统器械的非骨水泥型、保留交叉韧带初次全膝关节置换术:技术要点与术中注意事项
JBJS Essent Surg Tech. 2024 Sep 13;14(3). doi: 10.2106/JBJS.ST.23.00036. eCollection 2024 Jul-Sep.
3
[Proximal tibial replacement and alloplastic reconstruction of the extensor mechanism after bone tumor resection].[胫骨近端置换及骨肿瘤切除术后伸肌机制的异体修复重建]
Oper Orthop Traumatol. 2012 Jul;24(3):247-62. doi: 10.1007/s00064-012-0187-2.
4
Pedicled gastrocnemius flap: clinical application in limb sparing surgical resection of sarcoma around the knee region and popliteal fossa.带蒂腓肠肌皮瓣:在膝关节周围和腘窝肉瘤保肢手术切除中的临床应用
J Egypt Natl Canc Inst. 2008 Jun;20(2):196-207.
5
Surgical technique: extraarticular knee resection with prosthesis-proximal tibia-extensor apparatus allograft for tumors invading the knee.手术技术:关节外膝关节切除伴假体-胫骨近端-伸肌装置同种异体移植物,用于侵犯膝关节的肿瘤。
Clin Orthop Relat Res. 2011 Oct;469(10):2905-14. doi: 10.1007/s11999-011-1882-2. Epub 2011 Apr 12.
6
Melorheostosis: A Review of the Literature and a Case Report.骨硬化性黏液纤维瘤病:文献复习及病例报告。
Medicina (Kaunas). 2023 Apr 30;59(5):869. doi: 10.3390/medicina59050869.
7
Are Complications Associated With the Repiphysis(®) Expandable Distal Femoral Prosthesis Acceptable for Its Continued Use?与Repiphysis(®)可扩张股骨远端假体相关的并发症是否可接受其继续使用?
Clin Orthop Relat Res. 2015 Sep;473(9):3003-13. doi: 10.1007/s11999-015-4355-1. Epub 2015 May 21.
8
Medial gastrocnemius flap for reconstruction of knee extensor mechanism disruption after total knee replacement (TKR).内侧腓肠肌皮瓣用于全膝关节置换术后(TKR)膝关节伸肌机制断裂的重建。
Surg Technol Int. 2004;12:221-8.
9
What Is the Survival of the Telescope Allograft Technique to Augment a Short Proximal Femur Segment in Children After Resection and Distal Femur Endoprosthesis Reconstruction for a Bone Sarcoma?望远镜同种异体骨移植技术在儿童骨肿瘤切除和股骨远端假体重建后,用于增加短的股骨近端骨段的存活率如何?
Clin Orthop Relat Res. 2021 Aug 1;479(8):1780-1790. doi: 10.1097/CORR.0000000000001686.
10
What Are the Challenges and Complications of Sterilizing Autografts with Liquid Nitrogen for Malignant Bone Tumors? A Preliminary Report.用液氮对恶性骨肿瘤进行自体移植物消毒的挑战和并发症有哪些?初步报告。
Clin Orthop Relat Res. 2020 Nov;478(11):2505-2519. doi: 10.1097/CORR.0000000000001347.

本文引用的文献

1
Direct contact between tumor cells and platelets initiates a FAK-dependent F3/TGF-β positive feedback loop that promotes tumor progression and EMT in osteosarcoma.肿瘤细胞与血小板的直接接触会引发一个依赖于 FAK 的 F3/TGF-β 正反馈回路,从而促进骨肉瘤的肿瘤进展和 EMT。
Cancer Lett. 2024 Jun 1;591:216902. doi: 10.1016/j.canlet.2024.216902. Epub 2024 Apr 18.
2
Review of primary superficial soft tissue mesenchymal tumors of malignant or intermediate biological potential.恶性或具有中等生物学潜能的原发性浅表软组织间充质肿瘤的综述。
Skeletal Radiol. 2023 Mar;52(3):435-445. doi: 10.1007/s00256-022-04127-0. Epub 2022 Jul 22.
3
Overview of malignant soft-tissue sarcomas of the limbs.
四肢恶性软组织肉瘤概述。
Clin Radiol. 2021 Dec;76(12):940.e1-940.e16. doi: 10.1016/j.crad.2021.08.011. Epub 2021 Oct 1.
4
The rare primary bone sarcomas: imaging-pathological correlation.罕见的原发性骨肉瘤:影像学-病理学相关性。
Skeletal Radiol. 2021 Aug;50(8):1491-1511. doi: 10.1007/s00256-020-03692-6. Epub 2021 Jan 7.
5
Musculoskeletal Tumors.肌肉骨骼肿瘤。
Pediatr Clin North Am. 2020 Feb;67(1):227-245. doi: 10.1016/j.pcl.2019.09.014.
6
Distribution and evaluation of bone and soft tissue tumors operated in a tertiary care center.在三级医疗中心进行手术的骨与软组织肿瘤的分布及评估
Acta Orthop Traumatol Turc. 2019 May;53(3):189-194. doi: 10.1016/j.aott.2019.03.008. Epub 2019 Apr 11.
7
Sarcomas Associated With Genetic Cancer Predisposition Syndromes: A Review.与遗传性癌症易感性综合征相关的肉瘤:综述
Oncologist. 2016 Aug;21(8):1002-13. doi: 10.1634/theoncologist.2016-0079. Epub 2016 Jul 8.
8
Prevalence of bone and soft tissue tumors.骨与软组织肿瘤的患病率。
Acta Orthop Traumatol Turc. 2011;45(3):135-43. doi: 10.3944/AOTT.2011.2504.