• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一例与钠-葡萄糖协同转运蛋白2(SGLT2)抑制剂相关的正常血糖性糖尿病酮症酸中毒病例。

A Case of Euglycemic Diabetic Ketoacidosis Associated With a Sodium-Glucose Cotransporter-2 (SGLT2) Inhibitor.

作者信息

Hedary Antoine, Melder Lacie, Pippin Micah

机构信息

Family Medicine, Louisiana State University Health Sciences Center, Alexandria, USA.

出版信息

Cureus. 2024 Dec 9;16(12):e75399. doi: 10.7759/cureus.75399. eCollection 2024 Dec.

DOI:10.7759/cureus.75399
PMID:39781139
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11710868/
Abstract

Euglycemic diabetic ketoacidosis is a rare metabolic derangement seen in both type 1 and type 2 diabetes. Initially characterized decades ago, the prevalence of euglycemic diabetic ketoacidosis has increased in recent years following the introduction of sodium-glucose cotransporter-2 (SGLT2) inhibitors. Here, we present a case of euglycemic diabetic ketoacidosis associated with SGLT2 inhibitors.

摘要

正常血糖性糖尿病酮症酸中毒是1型和2型糖尿病中均可见的一种罕见代谢紊乱。几十年前首次被描述,近年来随着钠-葡萄糖协同转运蛋白2(SGLT2)抑制剂的应用,正常血糖性糖尿病酮症酸中毒的患病率有所增加。在此,我们报告一例与SGLT2抑制剂相关的正常血糖性糖尿病酮症酸中毒病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c830/11710868/c549c51b6223/cureus-0016-00000075399-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c830/11710868/ef5f94c826c7/cureus-0016-00000075399-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c830/11710868/c549c51b6223/cureus-0016-00000075399-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c830/11710868/ef5f94c826c7/cureus-0016-00000075399-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c830/11710868/c549c51b6223/cureus-0016-00000075399-i02.jpg

相似文献

1
A Case of Euglycemic Diabetic Ketoacidosis Associated With a Sodium-Glucose Cotransporter-2 (SGLT2) Inhibitor.一例与钠-葡萄糖协同转运蛋白2(SGLT2)抑制剂相关的正常血糖性糖尿病酮症酸中毒病例。
Cureus. 2024 Dec 9;16(12):e75399. doi: 10.7759/cureus.75399. eCollection 2024 Dec.
2
Euglycemic diabetic ketoacidosis associated with sodium-glucose cotransporter-2 inhibitor use: a case report and review of the literature.与钠-葡萄糖协同转运蛋白2抑制剂使用相关的正常血糖性糖尿病酮症酸中毒:一例病例报告及文献综述
Int J Emerg Med. 2019 Sep 5;12(1):27. doi: 10.1186/s12245-019-0240-0.
3
A Literature Review of the Therapeutic Perspectives of Sodium-Glucose Cotransporter-2 (SGLT2) Inhibitor-Induced Euglycemic Diabetic Ketoacidosis.钠-葡萄糖协同转运蛋白2(SGLT2)抑制剂诱发正常血糖性糖尿病酮症酸中毒治疗前景的文献综述
Cureus. 2022 Sep 27;14(9):e29652. doi: 10.7759/cureus.29652. eCollection 2022 Sep.
4
A Case of Prolonged Recovery for Post-percutaneous Coronary Intervention (PCI) Sodium-Glucose Cotransporter-2 (SGLT2) Inhibitor-Induced Euglycemic Diabetic Ketoacidosis in a 28-Year-Old.一例28岁经皮冠状动脉介入治疗(PCI)后因钠-葡萄糖协同转运蛋白2(SGLT2)抑制剂诱发正常血糖性糖尿病酮症酸中毒而长期恢复的病例
Cureus. 2023 Sep 13;15(9):e45180. doi: 10.7759/cureus.45180. eCollection 2023 Sep.
5
Sodium-glucose cotransporter-2 inhibitor-associated euglycemic diabetic ketoacidosis in COVID-19-infected patients: A systematic review of case reports.2019冠状病毒病感染患者中钠-葡萄糖协同转运蛋白2抑制剂相关的正常血糖性糖尿病酮症酸中毒:病例报告的系统评价
World J Clin Cases. 2023 Aug 26;11(24):5700-5709. doi: 10.12998/wjcc.v11.i24.5700.
6
Sodium-glucose cotransporter-2 (SGLT2) inhibitor-induced euglycemic diabetic ketoacidosis complicating the perioperative management of a patient with type 2 diabetes mellitus (T2DM) and Fournier's gangrene: A case report.钠-葡萄糖协同转运蛋白2(SGLT2)抑制剂诱发的正常血糖性糖尿病酮症酸中毒并发2型糖尿病(T2DM)合并福尼尔坏疽患者的围手术期处理:一例报告
Int J Surg Case Rep. 2020;77:463-466. doi: 10.1016/j.ijscr.2020.11.037. Epub 2020 Nov 11.
7
A Case of SGLT2 Inhibitor-Associated Euglycemic Diabetic Ketoacidosis Following Coronary Artery Bypass Surgery.冠状动脉搭桥术后发生SGLT2抑制剂相关的正常血糖性糖尿病酮症酸中毒1例。
AACE Clin Case Rep. 2020 Dec 28;7(1):20-22. doi: 10.1016/j.aace.2020.11.014. eCollection 2021 Jan-Feb.
8
Euglycemic diabetic ketoacidosis following traumatic brain injury.创伤性脑损伤后正常血糖性糖尿病酮症酸中毒
Am J Emerg Med. 2024 Mar;77:232.e1-232.e3. doi: 10.1016/j.ajem.2024.01.006. Epub 2024 Jan 9.
9
Euglycemic Diabetic Ketoacidosis With Prolonged Glucosuria Associated With the Sodium-Glucose Cotransporter-2 Canagliflozin.与钠-葡萄糖协同转运蛋白2抑制剂卡格列净相关的伴有长期糖尿的正常血糖性糖尿病酮症酸中毒
J Investig Med High Impact Case Rep. 2017 Jun 8;5(2):2324709617712736. doi: 10.1177/2324709617712736. eCollection 2017 Apr-Jun.
10
"Normal but Catastrophic" Euglycemic Diabetic Ketoacidosis Precipitated by Sodium-Glucose Cotransporter-2 Inhibitor Use: A Case Report.钠-葡萄糖协同转运蛋白2抑制剂使用引发的“正常但灾难性”的正常血糖性糖尿病酮症酸中毒:一例报告
Cureus. 2023 Nov 22;15(11):e49236. doi: 10.7759/cureus.49236. eCollection 2023 Nov.

引用本文的文献

1
Euglycemic diabetic ketoacidosis associated with a sodium-glucose co transporter 2 inhibitor use in a trauma patient: a case report.与钠-葡萄糖协同转运蛋白2抑制剂使用相关的正常血糖性糖尿病酮症酸中毒在一名创伤患者中的病例报告
Int J Emerg Med. 2025 Aug 13;18(1):152. doi: 10.1186/s12245-025-00963-8.
2
SGLT2 Inhibitors: From Structure-Effect Relationship to Pharmacological Response.钠-葡萄糖协同转运蛋白2(SGLT2)抑制剂:从构效关系到药理反应
Int J Mol Sci. 2025 Jul 19;26(14):6937. doi: 10.3390/ijms26146937.

本文引用的文献

1
Euglycemic diabetic ketoacidosis: A missed diagnosis.正常血糖性糖尿病酮症酸中毒:漏诊情况
World J Diabetes. 2021 May 15;12(5):514-523. doi: 10.4239/wjd.v12.i5.514.
2
Euglycemic diabetic ketoacidosis: a diagnostic and therapeutic dilemma.正常血糖性糖尿病酮症酸中毒:诊断与治疗难题
Endocrinol Diabetes Metab Case Rep. 2017 Sep 4;2017. doi: 10.1530/EDM-17-0081. eCollection 2017.
3
Ketoacidosis associated with SGLT2 inhibitor treatment: Analysis of FAERS data.与 SGLT2 抑制剂治疗相关的酮症酸中毒:FAERS 数据分析。
Diabetes Metab Res Rev. 2017 Nov;33(8). doi: 10.1002/dmrr.2924. Epub 2017 Sep 29.
4
An update on sodium-glucose co-transporter-2 inhibitors for the treatment of diabetes mellitus.钠-葡萄糖协同转运蛋白2抑制剂治疗糖尿病的最新进展
Curr Opin Endocrinol Diabetes Obes. 2017 Feb;24(1):73-79. doi: 10.1097/MED.0000000000000311.
5
Euglycemic Diabetic Ketoacidosis: A Predictable, Detectable, and Preventable Safety Concern With SGLT2 Inhibitors.正常血糖性糖尿病酮症酸中毒:SGLT2抑制剂相关的可预测、可检测且可预防的安全问题
Diabetes Care. 2015 Sep;38(9):1638-42. doi: 10.2337/dc15-1380.
6
Euglycemic Diabetic Ketoacidosis: A Potential Complication of Treatment With Sodium-Glucose Cotransporter 2 Inhibition.正常血糖性糖尿病酮症酸中毒:钠-葡萄糖协同转运蛋白2抑制剂治疗的一种潜在并发症。
Diabetes Care. 2015 Sep;38(9):1687-93. doi: 10.2337/dc15-0843. Epub 2015 Jun 15.
7
Inhibition of the glucose transporter SGLT2 with dapagliflozin in pancreatic alpha cells triggers glucagon secretion.用达格列净抑制胰岛α细胞中的葡萄糖转运蛋白 SGLT2 可触发胰高血糖素的分泌。
Nat Med. 2015 May;21(5):512-7. doi: 10.1038/nm.3828. Epub 2015 Apr 20.
8
Diabetic ketoacidosis: evaluation and treatment.糖尿病酮症酸中毒:评估与治疗。
Am Fam Physician. 2013 Mar 1;87(5):337-46.
9
Diagnostic accuracy of point-of-care testing for diabetic ketoacidosis at emergency-department triage: {beta}-hydroxybutyrate versus the urine dipstick.即时检测在急诊科分诊中诊断糖尿病酮症酸中毒的准确性:β-羟丁酸与尿干化学试带。
Diabetes Care. 2011 Apr;34(4):852-4. doi: 10.2337/dc10-1844. Epub 2011 Feb 9.
10
Euglycaemic diabetic ketoacidosis.正常血糖性糖尿病酮症酸中毒
Br Med J. 1973 Jun 9;2(5866):578-80. doi: 10.1136/bmj.2.5866.578.