Ghosh Shounak, Liang Bertrand
Department of Neurology, St. Joseph Medical Center, Stockton, USA.
Department of Neurology, University of Colorado, Colorado Springs, USA.
Cureus. 2024 Dec 9;16(12):e75368. doi: 10.7759/cureus.75368. eCollection 2024 Dec.
Cerebellar mutism syndrome (also known as posterior fossa syndrome) has been mostly seen in pediatric patients after surgery for neoplastic disease and is characterized by mutism, with variable symptoms such as emotional lability, ataxia, apraxia, and hypotonia. While the mechanism is not precisely defined, it is thought to result from disconnections between the cortical and cerebellar brain networks. Presentation in adult patients is rare, with various etiologies including posterior fossa ischemia, hemorrhage, and tumors being most reported. We report a case of adult-onset posterior fossa syndrome in a woman with a previous right hemisphere cerebellar stroke, in the context of contralateral cerebellar involvement and hypertensive urgency. The etiology, clinical presentation and course, and management of posterior fossa syndrome are discussed.
小脑缄默综合征（也称为后颅窝综合征）多见于患有肿瘤性疾病的小儿患者接受手术后，其特征为缄默，并伴有情绪不稳定、共济失调、失用症和肌张力减退等多种症状。虽然其机制尚未明确界定，但认为是由皮质和小脑脑网络之间的连接中断所致。成人患者中该综合征的表现较为罕见，最常报道的病因包括后颅窝缺血、出血和肿瘤。我们报告一例成年女性发生的后颅窝综合征，该患者既往有右侧半球小脑卒中史，此次发病伴有对侧小脑受累和高血压急症。本文讨论了后颅窝综合征的病因、临床表现及病程，以及治疗方法。
