Shogren Sophie L, Vivanco-Suarez Juan, Galecio-Castillo Milagros, Rodriguez-Calienes Aaron, Anil Susan, Alva Christian, Weng Julie, Smith Brian J, Torner James C, Mohr Nicholas M, Nigenda Vanessa Cano, Arauz Antonio, Ortega-Gutierrez Santiago
Department of Neurology, University of Iowa Hospitals and Clinics, Iowa City, IA, United States.
Department of Biostatics, the University of Iowa, Iowa City, IA, United States.
Int J Cerebrovasc Dis Stroke. 2024;7. doi: 10.29011/2688-8734.100185. Epub 2024 Aug 5.
Cerebral Venous Sinus Thrombosis (CVST) is a relatively rare type of stroke, accounting for less than 3% of all stroke cases, and is associated with significant morbidity and mortality in young females. However, when promptly diagnosed and treated, it can have favorable outcomes. Several knowledge gaps remain regarding pathophysiology, diagnosis, and management of CVST, so critical assessment of past and present research could help close these gaps or establish targeted future research goals.
We screened Elsevier Scopus database articles with CVST as the primary topic. Clinical guidelines, abstracts, letters, and editorials were excluded. The top 100 articles, ordered by number of citations, were selected, and data collection and analysis were performed using Microsoft Excel, R software, and VOS viewer.
Out of 4,832 documents, the top 100 most-cited articles spanned the years of 1973 to 2021 and had a total citation frequency of 18,208. France and the United States were the top-contributing countries, and Stroke had the highest number of manuscripts published in the top 100 (n=30). Analysis of word-use trends over time showed increases in the mention of "vaccination" since 2021, "mechanical thrombectomy" since 2017, and "fibrinolytic therapy" since 2015.
Our study detailed the 100 most-cited articles on CVST in the past 50 years. Understanding top-contributing countries, authors, and journals may help guide the direction of future research in CVST and encourage collaboration within the field. Areas of further research may include association with other pathologies (non-infectious and infectious) and advancements in acute therapies.
脑静脉窦血栓形成（CVST）是一种相对罕见的中风类型，占所有中风病例的不到3%，并且在年轻女性中与显著的发病率和死亡率相关。然而，如果能及时诊断和治疗，可能会有良好的预后。关于CVST的病理生理学、诊断和管理仍存在一些知识空白，因此对过去和当前研究的批判性评估有助于填补这些空白或确立有针对性的未来研究目标。
我们在爱思唯尔Scopus数据库中筛选以CVST为主要主题的文章。排除临床指南、摘要、信件和社论。选择按引用次数排序的前100篇文章，并使用微软Excel、R软件和VOS viewer进行数据收集和分析。
在4832篇文献中，前100篇被引用次数最多的文章跨越1973年至2021年，总引用频率为18208次。法国和美国是贡献最大的国家，《中风》杂志在前100篇文章中发表的稿件数量最多（n = 30）。对随时间的词汇使用趋势分析表明，自2021年以来“疫苗接种”的提及有所增加，自2017年以来“机械取栓术”的提及有所增加，自2015年以来“纤维蛋白溶解疗法”的提及有所增加。
我们的研究详细介绍了过去50年中关于CVST的100篇被引用次数最多的文章。了解贡献最大的国家、作者和期刊可能有助于指导CVST未来的研究方向，并鼓励该领域内的合作。进一步研究的领域可能包括与其他病理状况（非感染性和感染性）的关联以及急性治疗的进展。
