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支架取栓联合中间导管抽吸治疗难治性重症脑静脉窦血栓形成

Mechanical Thrombectomy with Tandem Double Stent Retriever in Combination with Intermediate Catheter Aspiration for Refractory Severe Hemorrhagic Cerebral Venous Sinus Thrombosis.

机构信息

Department of Neurosurgery, Neurosurgery Research Institute, The First Affiliated Hospital, Fujian Medical University, Fuzhou, China.

Department of Neurosurgery, Neurosurgery Research Institute, The First Affiliated Hospital, Fujian Medical University, Fuzhou, China; Fujian Provincial Clinical Research Center for Neurological Disease, The First Affiliated Hospital, Fujian Medical University, Fuzhou, China; Department of Neurosurgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, China; Fujian Provincial Institutes of Brain Disorders and Brain Sciences, The First Affiliated Hospital, Fujian Medical University, Fuzhou, China; Clinical research and translation center, the First Affiliated Hospital, Fujian Medical University, Fuzhou, China.

出版信息

World Neurosurg. 2022 Nov;167:e990-e997. doi: 10.1016/j.wneu.2022.08.123. Epub 2022 Sep 2.

Abstract

OBJECTIVE

We aimed to describe the initial experience of mechanical thrombectomy using tandem double stent retrievers combined with intermediate catheter aspiration to treat refractory severe hemorrhagic (SH)-cerebral venous sinus thrombosis (CVST).

METHODS

All refractory SH-CVST patients treated with mechanical thrombectomy using tandem double stent retriever (SR) combined with intermediate catheter aspiration (MT-TDSA) in our institution were retrospectively reviewed. MT-TDSA is a technique that fully engages the clot with double SRs and retrieves the clot using a double SR in combination with aspiration from an intermediate catheter. Demographics, clinical manifestation, medical history, the location of the occluded venous sinus, intraoperative details, procedure-related complications, and modified Rankin Scale (1, 6, 12 months postoperatively) were collected and analyzed.

RESULTS

Fourteen patients (median age, 43 years) with refractory SH-CVST were treated with MT-TDSA between January 2016 and January 2020. Ten of 14 (71.4%) had a successful intraoperative recanalization rate (>90%) using MT-TDSA. No procedure-related complications occurred. Eleven patients had good clinical outcomes (modified Rankin Scale score 0-2 at 12 months postoperatively).

CONCLUSIONS

MT-TDSA for refractory SH-CVST might improve clot-capturing ability and remove blood clots from cerebral venous sinuses effectively and safely, achieving good clinical outcomes.

摘要

目的

我们旨在描述使用串联双支架取栓器联合中间导管抽吸治疗难治性重度出血性(SH)-脑静脉窦血栓形成(CVST)的机械血栓切除术的初步经验。

方法

回顾性分析了我院采用串联双支架取栓器(SR)联合中间导管抽吸(MT-TDSA)治疗的所有难治性 SH-CVST 患者。MT-TDSA 是一种充分结合双 SR 以捕捉血栓并通过双 SR 联合中间导管抽吸来清除血栓的技术。收集并分析了人口统计学、临床表现、病史、闭塞静脉窦的位置、手术过程中的细节、与手术相关的并发症以及改良 Rankin 量表(术后 1、6、12 个月)。

结果

2016 年 1 月至 2020 年 1 月期间,采用 MT-TDSA 治疗难治性 SH-CVST 的 14 例患者(中位年龄为 43 岁)中,10 例(71.4%)患者术中再通率(>90%)达到成功。没有发生与手术相关的并发症。11 例患者具有良好的临床转归(术后 12 个月改良 Rankin 量表评分为 0-2)。

结论

MT-TDSA 治疗难治性 SH-CVST 可能会提高血栓捕捉能力,并有效、安全地从脑静脉窦中清除血栓,从而获得良好的临床转归。

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